Results 81 to 90 of about 3,575,013 (348)

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source

ORNE Learning Model to Improve Problem-Solving Skills of Physics Bachelor Candidates: An Alternative Learning in the Covid-19 Pandemic

Jurnal Penelitian Fisika dan Aplikasinya, 2020
In this industrial revolution 4.0 era, professional science, technology, engineering, and mathematics (STEM) bachelor must have various skills. One of which is problem-solving skills.
Binar Kurnia Prahani, Ali Hasbi Ramadani, Diah Hari Kusumawati, Nadi Suprapto, Madlazim Madlazim, Budi Jatmiko, Zainal Arifin Imam Supardi, Husni Mubarok, Shabrina Safitri, Utama Alan Deta   +9 more
doaj   +1 more source

Pembinaan modul berasaskan web untuk meningkatkan kemahiran metakognitif dalam penyelesaian masalah fizik [PDF]

, 2015
Problem solving plays a major role in Physics instruction. However, traditional instruction is unable to improve Physics problem solving skills. Studies show that web-based learning can enhance Physics problem solving skills, thus the student achievement
Ali, Marlina, Ibrahim, Nor Hasniza, Saim, Nurshamela   +2 more
core  

Teaching Problem Solving Skills using an Educational Game in a Computer Programming Course

Informatics Educ., 2019
Problem solving skills are considered an important component in learning to program in an introductory programming (IP) course for novices. This study introduced a PROSOLVE game to enhance problem solving skills of novice programmers in the introductory ...
R. Mathew, S. I. Malik, R. M. Tawafak
semanticscholar   +1 more source

Collaborative Problem-based Learning: An Analysis of Problem-Solving Skills in Vocational Schools

IJORER : International Journal of Recent Educational Research, 2020
This study aims to analyze the effect of using Collaborative Problem-Based Learning (CPBL) on students' problem-solving skills. This study used a 2x2 factorial design, in which the selection of experimental and control groups was determined with ...
R. Hidayatullah, S. Ariyanto, Muhaji, Husni Mubarok, Abebayehu Yohannes   +4 more
semanticscholar   +1 more source

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

FEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini, Nicolò Antonelli, Gianluca Molla   +2 more
wiley   +1 more source

Student Engagement in Law School: Preparing 21st Century Lawyers [PDF]

, 2009
Presents findings from an annual survey, with a focus on teaching and learning methods that help students develop as ethical professionals and improve their legal writing and problem-solving ...

core  

Problem-solving skills and suicidal ideation among Malaysian college students: the mediating role of hopelessness [PDF]

, 2015
Objective: Recent evidence suggests that suicidal ideation has increased among Malaysian college students over the past two decades; therefore, it is essential to increase our knowledge concerning the etiology of suicidal ideation among Malaysian college
Abdollahi, Abbas, Abu Talib, Mansor, Ismail, Zanariah, Yaacob, Siti Nor   +3 more
core   +1 more source

Dietary nitrate and nitrite protect against doxorubicin‐induced cardiac fibrosis and oxidative protein damage in tumor‐bearing mice

FEBS Open Bio, EarlyView.
Chemotherapies such as doxorubicin can have toxic effects on healthy cardiovascular/heart tissue. Following up on a doxorubicin toxicity study in mice without tumors where nitrate water was cardioprotective (lessened toxicity), this study with tumor‐bearing mice undergoing doxorubicin treatment showed no negative effect of nitrate and nitrite on drug ...
Rama D. Yammani, Xiaofei Chen, Nildris Cruz‐Diaz, Xuewei Zhu, Swati Basu, Daniel B. Kim‐Shapiro, David R. Soto‐Pantoja, Leslie B. Poole   +7 more
wiley   +1 more source

Elevating Teachers’ Competence through the Development of Instructional Media Oriented to Problem-solving Skills with the Aid of Articulate Storyline

Engagement: Jurnal Pengabdian Kepada Masyarakat
With rapid technological advancement, integrating technology into education becomes increasingly important. It is thus imperative for teachers to master satisfactory competence in improving students' problem-solving skills.
Rafiantika Megahnia Prihandini, Susi Setiawani, Yuli Feri Widyawati   +2 more
doaj   +1 more source