Results 51 to 60 of about 531,018 (236)

Problematic Internet Use: A Longitudinal Study Evaluating Prevalence and Predictors

The Journal of Pediatrics: X, 2019
Objective: To assess the prevalence over time and predictors of problematic internet use using the Problematic and Risky Internet Use Screening Scale (PRIUSS). We also identified an intermediate-risk PRIUSS score.
Megan A. Moreno, MD, MSEd, MPH, Jens Eickhoff, PhD, Qianqian Zhao, MS, Henry N. Young, PhD, Elizabeth D. Cox, PhD   +4 more
doaj   +1 more source

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

Molecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller, Susanne Ebner, Carmen Haselrieder, Julia K. Günther, Astrid Drasche, Sophie Strich, Chiara Volani, Andrea Medici, Aleksandar Nikolajevic, Alex Deltedesco, Johannes E. Sigmund, Michael J. Blumer, Martin Hermann, Johanna Vanacker, Gerald Brandacher, Eduard Stefan, Omar Torres‐Quesada, Jakob Troppmair   +17 more
wiley   +1 more source

Makna Internet Bagi Individu Dengan Problematic Internet Use [PDF]

, 2013
Penelitian ini bertujuan untuk menggambarkan makna internet dari individu dengan Problematic Internet Use (PIU), melalui pemahaman atas latar belakang, proses, serta dampak psikologis yang dialami.Penelitian ini menggunakan metode kualitatif ...
Dewi, K. S. (Kartika), Wardanie, F. (Fithria)   +1 more
core  

Screening for Adolescent Problematic Internet Use: Validation of the Problematic and Risky Internet Use Screening Scale (PRIUSS) [PDF]

Academic Pediatrics, 2015
Problematic Internet use (PIU) is an emerging health concern that lacks screening measures validated for use with adolescents and young adults. This study aimed to validate the Problematic and Risky Internet Use Screening Scale (PRIUSS) for use with older adolescents and to increase its clinical utility by determining scoring guidelines and assessing ...
Lauren A, Jelenchick, Jens, Eickhoff, Chong, Zhang, Kristina, Kraninger, Dimitri A, Christakis, Megan A, Moreno   +5 more
openaire   +2 more sources

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

Molecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

Diagnostic Criteria for Problematic Internet Use among U.S. University Students: A Mixed-Methods Evaluation.

PLoS ONE, 2016
Empirical studies have identified increasing rates of problematic Internet use worldwide and a host of related negative consequences. However, researchers disagree as to whether problematic Internet use is a subtype of behavioral addiction.
Wen Li, Jennifer E O'Brien, Susan M Snyder, Matthew O Howard   +3 more
doaj   +1 more source

The association between parent-child relationship and problematic internet use among English- and Chinese-language studies: A meta-analysis

Frontiers in Psychology, 2022
As past studies of the association between parent-child relationship and problematic internet use show mixed results and are influenced by many factors, this meta-analysis of 75 primary Chinese and English language studies from 1990 to 2021 with 110,601 ...
Yalin Zhu, Yalin Zhu, Linyuan Deng, Kun Wan   +3 more
doaj   +1 more source

Utility of Parental Mediation Model on Youth’s Problematic Online Gaming [PDF]

, 2015
The Parental Mediation Model PMM) was initially designed to regulate children’s attitudes towards the traditional media. In the present era, because of prevalent online media there is a need for similar regulative measures.
A Daud, A Kapahi, A Nathanson, AI Nathanson, AK Liau, BM Byrne, D Hooper, DA Fisher, DTL Shek, G Mesch, HF Kaiser, JF Hair, LA Kirkpatrick, M Buijzen, M Buijzen, M Teimori, Mark D. Griffiths, Misha Teimouri, MO Lwin, NAM Zin, P Nikken, PM Valkenburg, Rahim Benrazavi, RB Kline, S-J Lee, S-J Lee, Y Fujioka, Z Demetrovics   +27 more
core   +1 more source

Applicability of mitotic figure counting by deep learning: a development and pan‐cancer validation study

FEBS Open Bio, EarlyView.
In this study, we developed a deep learning method for mitotic figure counting in H&E‐stained whole‐slide images and evaluated its prognostic impact in 13 external validation cohorts from seven different cancer types. Patients with more mitotic figures per mm2 had significantly worse patient outcome in all the studied cancer types except colorectal ...
Joakim Kalsnes, Maria X. Isaksen, Frida Julbø, Manohar Pradhan, Andreas Kleppe, Sepp De Raedt, Ole‐Johan Skrede, Turid Torheim, John Arne Nesheim, Hans Martin Mohn, Hanne A. Askautrud, Karolina Cyll, Wanja Kildal, Emma Rewcastle, Melinda Lillesand, Vebjørn Kvikstad, Emiel Janssen, Robert Jones, Odd Terje Brustugun, Bjørn Brennhovd, Erik Skaaheim Haug, Lill‐Tove Rasmussen Busund, Elin Richardsen, Sigve Andersen, Tom Dønnem, Kristina Lindemann, Gunnar Kristensen, Neil A. Shepherd, Marco Novelli, Knut Liestøl, David Kerr, Håvard E. Danielsen, Tarjei S. Hveem   +32 more
wiley   +1 more source

Personality, fear of missing out and problematic internet use and their relationship to subjective well-being [PDF]

, 2017
The current research examines how an individual’s personality, their internet use and the extent to which they are inclined to fear ‘missing out’ impacts subjective well-being overall and in terms of emotional, physical, and personal relationship well ...
Bibby, Peter A., Stead, Holly
core   +2 more sources