Results 51 to 60 of about 32,725,349 (248)

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

Distinct Profiles of Problematic Smartphone and Social Media Use Among French University Students: A Person-Centered Analysis of Sociodemographic, Psychological, Social, and Academic Correlates

Psychiatry International
Background: Problematic smartphone use (PSU) and problematic social media use (PSMU) are common among university students, but little is known about whether distinct patterns of use exist. This study identified profiles of smartphone and social media use
Germano Vera Cruz, Clarice Da Rosa
doaj   +1 more source

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

Molecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu, Yubei He, Nikolaus Berndt, Michael Mülleder, Kathrin Textoris‐Taube, Jing Guo, Matthias Stechele, Justus Ramtke, Shraga Nahum Goldberg, Lynn Jeanette Savic   +9 more
wiley   +1 more source

Data Deception Behavior, Fear of Missing Out, Personality, and Problematic Social Media Use

, 2022
Data Deception Behavior, Fear of Missing Out, Personality, and Problematic Social Media ...
Clara Moningka (13846514), Silverius Y. Soeharso (12650101), Selviana Selviana (13846511), Resy Sundari (12650104), Lisa Dwi Ningtyas (12220130)   +4 more
core   +1 more source

Problematic Social Media Use for Mood Modification: Its Associations with Shame, Guilt, Anger, and Difficulties in Emotion Regulation

Addicta: The Turkish Journal on Addictions, 2021
Problematic social media use is increasingly becoming one of the major concerns of both the research and clinic community. Social media can be used as a way of emotion regulation since it is a powerful tool for getting acceptance and support from others.
Merve Denizci Nazlıgül, Özge Koçyiğit, Ezgi Didem Merdan Yıldız   +2 more
doaj   +1 more source

Characterization of therapeutic antibodies targeting lymphatic and vascular resistance factor for the treatment of hypervascularized and highly metastatic cancers

Molecular Oncology, EarlyView.
LVRF (lymphatic and vascular resistance factor) is a VEGFA splice variant upregulated in response to anti‐angiogenic therapy that fosters tumor adaptation through enhanced vascularization, lymphangiogenesis, and metastatic dissemination. Targeting LVRF with fully human neutralizing antibodies disrupts these processes and limits resistant tumor growth ...
Marion David, Arthur Karaulic, Audrey Bennetot, Clémence Fournier, Quentin Odet, Arthur Gouraud, Isabelle Bourget, Cédric Gaggioli, Sandy Giuliano, Frédéric Luciano, Olivier Léger, Zaki Sellam, Gilles Pagès   +12 more
wiley   +1 more source

The relationship between problematic digital media use and food addiction, eating behaviours, and obesity: a cross-sectional study on Turkish university students

BMC Psychology
Background Problematic use of social media and smartphones has been increasingly linked to unhealthy lifestyle behaviors and weight-related problems. However, limited evidence exists on how these digital behaviors are associated with food addiction and ...
Hakan Toğuç
doaj   +1 more source

Effect of emotional intelligence on problematic mobile social media use: mediating role of peer relationships and experiential avoidance

Frontiers in Psychology
ObjectiveThe I-PACE model was employed as the theoretical framework to investigate the effect of emotional intelligence on problematic mobile social media use.
Xin Chen, Sifan Peng, Hexu Guan, Huanran Sun, Hongxuan Wu, Xumei Yao, Zi Chen, Xi Yang   +7 more
doaj   +1 more source

Identifying and characterising a plant GH1 β‐glucosidase that exhibits hydrolytic activity on N‐linked glucopyranoside

FEBS Open Bio, EarlyView.
We report the first β‐glucosidase with demonstrated hydrolytic activity on an N‐linked glycopyranoside. The enzyme, native to maize, was biochemically characterised for this novel reaction, and structural modelling of the enzyme–substrate complex revealed several clues to the underlying reduced catalytic rate relative to its native O‐glycopyranoside ...
Hani Gharabli, Carlotta Chiesa, Maher Abou Hachem, Ditte Hededam Welner   +3 more
wiley   +1 more source

Effect of emotional intelligence on problematic social media use among Chinese college students: mediating role of social exclusion and experiential avoidance

Frontiers in Psychiatry
ObjectiveTo examine the mediating effects of social exclusion and experiential avoidance on college students’ emotional intelligence and problematic social media use.MethodsUsing convenience sampling, 1,448 students enrolled at nine public universities ...
Hexu Guan, Sifan Peng, Zixin Liu, Huanran Sun, Hongxuan Wu, Xumei Yao, Zi Chen, Xi Yang   +7 more
doaj   +1 more source