Results 61 to 70 of about 7,460,081 (292)

The athlete as a problem in the olympic movement and the approaches to solve it. [PDF]

open access: yesPedagogìka, Psihologìâ ta Mediko-bìologìčnì Problemi Fìzičnogo Vihovannâ ì Sportu, 2011
Basic problems which pursue a sportsman in olympic sport are considered. Over 30 informative sources of domestic and foreign authors are analysed. The analysis of modern scientific, scientifically-methodical literature and informative information allowed
Voropay Sergej Nikolaevich
doaj  

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

open access: yesMolecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur   +11 more
wiley   +1 more source

Problems Experienced in the First Month After Discharge From a Heart Failure-Related Hospitalization

open access: yesJournal of Patient-Centered Research and Reviews, 2018
Purpose: Heart failure is a global health concern with high morbidity and mortality rates. Individuals with heart failure commonly experience problems that impact daily life.
Joan S. Grant   +2 more
doaj   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

open access: yesMolecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

The Problem with the Problem of Consciousness

open access: yesSynthesis philosophica, 2008
This paper proposes that the ‘problem of consciousness’, in its most popular formulation, is based upon a misinterpretation of the structure of experience. A contrast between my subjective perspective (A) and the shared world in which I take up that perspective (B) is part of my experience.
openaire   +3 more sources

Nonlinear problems : present and future : proceedings of the first Los Alamos Conference on Nonlinear Problems, Los Alamos, NM, U.S.A., March 2-6, 1981 /

open access: yes, 1982
Nonlinear Problems: Present and Future.Includes bibliographical references and index.Print version record.Front Cover; Nonlinear Problems: Present and Future; Copyright Page; PREFACE; DEDICATION; TABLE OF CONTENTS; PART I : NEW METHODS AND RESULTS IN ...
Campbell, David K.   +3 more
core  

Spatial biology in cancer epigenetics

open access: yesMolecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

PERSPECTIVE DEVELOPMENT DIRECTIONS WITHIN SEZ IN THE REPUBLIC OF CRIMEA AND SEVASTOPOL CITY

open access: yesМодернизация, инновация, развитие, 2016
The subject of the article is perspective development directions within special economic zone in Republic of Crimea and Sevastopol city. After holding the referendum on joining of the peninsula to the Russian Federation, the leadership of the country ...
P. P. Bogdanenko
doaj  

Diagnosing Problems - Raw Materials

open access: yes, 2011
The raw materials which make up the Diagnosing Problems learning activity which introduces the concept of problem diagnosis and offers techniques and tools to find problem causes.
EVOLUTION   +4 more
core  

ADP‐ribosylation: An emerging regulator of the epigenome

open access: yesMolecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho   +2 more
wiley   +1 more source

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