Results 61 to 70 of about 16,116 (276)

Systems Pharmacology [PDF]

open access: yes, 2008
The slides are from a presentation given by Professor Ravi Iyengar from Mount Sinai School of Medicine at the Drug Forum Meeting #9 that took place in Washington, DC on February 20-21, 2008.
Ravi Iyengar
core   +2 more sources

Brugada Syndrome or Phenocopy? Diagnostic Challenge in Patients with Pectus Excavatum

open access: yesJournal of Cardiac Arrhythmias, 2020
Brugada syndrome is an autosomal dominant heart disease caused by dysfunctions in the ionic channels, whose carriers present a classic electrocardiographic pattern and predisposition to malignant ventricular arrhythmias. The electrocardiogram alterations
Kárila Scarduelli Luciano   +3 more
doaj   +4 more sources

Coexistence of Atrioventricular Nodal Reentrant Tachycardia and Idiopathic Left Ventricular Outflow-Tract Tachycardia [PDF]

open access: yes, 2005
Double tachycardia is a relatively rare condition. We describe a 21 year old woman with history of frequent palpitations. In one of these episodes, she had wide complex tachycardia with right bundle branch and inferior axis morphology.
Arya, Arash   +6 more
core   +2 more sources

ECG Markers of Positive Drug Challenge With Ajmaline in Patients With Brugada Syndrome

open access: yesAnnals of Noninvasive Electrocardiology, Volume 31, Issue 1, January 2026.
A prominent S‐wave in lead II on a nondiagnostic baseline ECG is a powerful predictor for unmasking Brugada syndrome during an ajmaline challenge. This subtle sign enhances patient selection for provocation testing and aids in risk stratification, particularly in familial screening.
Erol Tülümen   +9 more
wiley   +1 more source

Molecular modeling studies of the novel inhibitors of DNA methyltransferases SGI-1027 and CBC12: implications for the mechanism of inhibition of DNMTs. [PDF]

open access: yesPLoS ONE, 2013
DNA methylation is an epigenetic modification that regulates gene expression by DNA methyltransferases (DNMTs). Inhibition of DNMTs is a promising approach for cancer therapy.
Jakyung Yoo   +2 more
doaj   +1 more source

Development Of An Inhibitive Acetylcholinesterase-Based Assay For Insecticides [PDF]

open access: yes, 2008
An inhibition study on Pangasius pangasius brain Acetylcholinesterase (AChE) was conducted. A custom-synthesized affinity column chromatography utilizing activated Sephacryl S-1000 was successfully coupled to procainamide. AChE loaded onto the column and
Tham, Lik Gin
core   +1 more source

Pauci-immune glomerulonephritis in individuals with disease associated with levamisole-adulterated cocaine: a series of 4 cases. [PDF]

open access: yes, 2014
Exposure to levamisole-adulterated cocaine can induce a distinct clinical syndrome characterized by retiform purpura and/or agranulocytosis accompanied by an unusual constellation of serologic abnormalities including antiphospholipid antibodies, lupus ...
Butcher, Brad   +6 more
core   +2 more sources

Myasthenia Gravis Outcomes After Use of Statins and Other Contraindicated Treatments: Results From the French National Insurance Database

open access: yesEuropean Journal of Neurology, Volume 33, Issue 1, January 2026.
In this real‐world study among 14,459 adults with MG, exposure to any contraindicated treatment was not significantly associated with risk of ICU admission for MG but was associated with significantly higher risk of death. In contrast, statins were associated with a greater risk of ICU admission but a lower risk of death.
Guilhem Solé   +7 more
wiley   +1 more source

Pharmacologic pitfalls in heart failure: A guide to drugs that may cause or exacerbate heart failure. A European Journal of Heart Failure expert consensus document

open access: yesEuropean Journal of Heart Failure, Volume 27, Issue 12, Page 2671-2690, December 2025.
Main categories of harmful drugs in heart failure. CCB, calcium channel blocker; DPP4i, dipeptidyl peptidase‐4 inhibitor; HER2‐TT, human epidermal growth factor receptor 2‐targeted therapy; NSAID, non‐steroidal anti‐inflammatory drug; TKI, tyrosine kinase inhibitor; TZD, thiazolidinedione; VEGF Inh, vascular endothelial growth factor inhibitor.
Amr Abdin   +16 more
wiley   +1 more source

The Concise Guide to PHARMACOLOGY 2025/26: G protein‐coupled receptors

open access: yesBritish Journal of Pharmacology, Volume 182, Issue S1, Page S24-S151, December 2025.
The Concise Guide to Pharmacology 2025/26 marks the seventh edition in this series of biennial publications in the British Journal of Pharmacology. Presented in landscape format, the guide provides a comparative overview of the pharmacology of drug target families. The concise nature of the Concise Guide refers to the style of presentation, being clear,
Stephen P. H. Alexander   +206 more
wiley   +1 more source

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