Results 61 to 70 of about 10,489 (201)
Myocardial toxicity in two dogs with natural exposure to ractopamine
Abstract Two dogs that lived in a farm setting were presented to the Texas A&M University Veterinary Medical Teaching Hospital's Emergency Service exhibiting muscle tremors and ventricular arrhythmias following ingestion of ractopamine, a ß‐2 agonist feed‐additive used in beef cattle, pigs and turkeys intended for slaughter to increase muscle mass. The
Sophie Tippit +3 more
wiley +1 more source
Molecular modeling studies of the novel inhibitors of DNA methyltransferases SGI-1027 and CBC12: implications for the mechanism of inhibition of DNMTs. [PDF]
DNA methylation is an epigenetic modification that regulates gene expression by DNA methyltransferases (DNMTs). Inhibition of DNMTs is a promising approach for cancer therapy.
Jakyung Yoo +2 more
doaj +1 more source
Therapeutic and toxic blood concentrations of nearly 1,000 drugs and other xenobiotics [PDF]
Introduction: In order to assess the significance of drug levels measured in intensive care medicine, clinical and forensic toxicology, as well as for therapeutic drug monitoring, it is essential that a comprehensive collection of data is readily ...
Andresen, Hilke +3 more
core +1 more source
PharmVar GeneFocus: NAT2—Genetic Variation and Updated Nomenclature
The Pharmacogene Variation Consortium (PharmVar) provides nomenclature for the highly polymorphic human N‐acetyltransferase 2 (NAT2) gene. NAT2 metabolizes several clinically used drugs including isoniazid, hydralazine, amifampridine, procainamide, and sulfonamides such as dapsone, and also some highly carcinogenic arylamines.
Georgia Papanikolaou +14 more
wiley +1 more source
Etanercept and venous thromboembolism: a case series [PDF]
Introduction The treatment with antitumor necrosis factor agents has often been associated with the induction of autoantibodies (antinuclear antibodies, anti-double stranded DNA antibodies and antiphospholipid antibodies).
Ashima Makol +12 more
core +2 more sources
In a real‐world emergency department study of atrial fibrillation and flutter, cardioversion restored sinus rhythm in 68% of patients. Electrical cardioversion achieved the highest success, while pharmacological and mixed strategies predicted failure. Complications were infrequent but clinically significant.
Abid M. Sadiq +3 more
wiley +1 more source
The contribution of epigenetics in Sjögren's Syndrome. [PDF]
International audience: Sjögren's syndrome (SS) is a chronic autoimmune epithelitis that combines exocrine gland dysfunctions and lymphocytic infiltrations.
Athanasios G Tzioufas +8 more
core +4 more sources
Lung cancer (LC) remains the leading cause of global cancer‐related death. Phytochemicals from medicinal plants are increasingly being considered as potential LC treatment agents due to their multi‐targeted action, safety, and accessibility. These have anticancer properties by regulating key molecular signaling pathways.
Md. Rezaul Islam +14 more
wiley +1 more source
Role of pharmacotherapy in Brugada syndrome [PDF]
In patients who undergo aborted sudden cardiac death or syncope of unknown origin (symptomatic Brugada syndrome), no one argues that the implantation of an ICD is the first-line therapy regardless of the findings of the EP study.
Tsuchiya, Takeshi
core +1 more source
Objective Glucagon‐like peptide 1 receptor agonists (GLP‐1RAs) and sodium‐glucose cotransporter 2 inhibitors (SGLT2i) facilitate weight loss and exhibit immunomodulatory effects, but their impact on the risk of developing autoimmune rheumatic diseases (ARDs) is unclear.
Derin Karacabeyli +4 more
wiley +1 more source

