Results 71 to 80 of about 19,445 (231)

4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase in malaria parasites and enhances atovaquone efficacy

FEBS Letters, Volume 600, Issue 2, Page 251-266, January 2026.
Atovaquone is an antimalarial requiring potentiation for sufficient efficacy. We pursued strategies to enhance its activity, showing that 4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase, decreasing ubiquinone biosynthesis. Since atovaquone competes with ubiquinol in mitochondria, 4‐nitrobenzoate facilitates its action, potentiating ...
Ignasi Bofill Verdaguer, Matheus Felipe Santos, Maurício Mazzine Filho, Gabriela Oliveira Castro, Agustín Hernández, Manoel Aparecido Peres, Alejandro Miguel Katzin, Marcell Crispim   +7 more
wiley   +1 more source

Terapia neural perivascular e intravascular ecoguiada. Revisión bibliográfica

Revista GICOS
La terapia neural, también conocida como medicina neural terapéutica o acupuntura alemana, es una técnica terapéutica creada por los hermanos Ferdinand y Walter Huneke en el año 1925 que consiste en la inyección de anestésicos locales para la resolución ...
Mariam Pino-Valbuena, Jesús Alejandro López-Silva, Omar Balza, Cristian Pino-Valbuena, Carmen Elena Salas-Vera   +4 more
doaj   +1 more source

Batch and flow injection spectrophotometric determination of procaine-HCl using diazotization-coupling reaction

Journal of Basic and Applied Research in Biomedicine, 2022
This paper involves batch and flow injection spectrophotometric determination of procaine-hydrochloride in pharmaceutical formulations. These methods were based on the diazotization reaction of procaine-HCl with sodium nitrite and hydrochloric acid to ...
Kamal Mahmoud, Suzan Taha
doaj  

Simplified antibiotic regimens for treatment of clinical severe infection in the outpatient setting when referral is not possible for young infants in Pakistan (Simplified Antibiotic Therapy Trial [SATT]): a randomised, open-label, equivalence trial

The Lancet Global Health, 2017
Background: Parenteral antibiotic therapy for young infants (aged 0–59 days) with suspected sepsis is sometimes not available or feasible in countries with high neonatal mortality. Outpatient treatment could save lives in such settings.
Dr. Fatima Mir, MBBS, Imran Nisar, MBBS, Shiyam S Tikmani, MBBS, Benazir Baloch, MBBS, Sadia Shakoor, MBBS, Fyezah Jehan, MBBS, Imran Ahmed, MSc, Simon Cousens, DipMathStat, Prof. Anita K M Zaidi, MD   +8 more
doaj   +1 more source

Supracubital perineurioma misdiagnosed as carpal tunnel syndrome: case report

BMC Neurology, 2004
Background Perineuriomas have been defined as tumorous lesions of the peripheral nerves which derive from perineurial cell proliferation and may be associated with abnormalities on chromosome 22. Case presentation Three years after a painful cubital vein
Schols Ludger, Schmid Gebhard, Neuen-Jacob Eva, Andrich Juergen E, Saft Carsten, Amoiridis Georgios   +5 more
doaj   +1 more source

Comparison of Clinical Outcomes of Two Different Cardioplegic Solutions in Patients Undergoing Coronary Artery Bypass Graft Surgery; A randomize clinical trial

Advanced Biomedical Research
Background: Usually, manual cardioplegic solutions with low magnesium and lidocaine, and corporate solutions with high magnesium and procaine, are the only common solutions used to induce cardiac arrest during coronary artery bypass graft (CABG) surgery.
Alireza Hosseini, Mehran Shahzamani, Asieh Maghami-Mehr, Farzin Khosravi, Nafiseh Emadi   +4 more
doaj   +1 more source

Dual Electrochemical Methods for Determination of Anesthetic Procaine

ARO-The Scientific Journal of Koya University
Procaine belongs to a type of medicine in which excessive dosage form creates cardiac problems and many allergenic reactions. Thus, continuous monitoring of this drug and its metabolite is crucial for sustainable health management during treatment.
Gulan S. Qadir, Amer T. Al-Taee, Nabeel S. Othman   +2 more
doaj   +1 more source

Synthesis of procaine analogues containing pentafluoroethoxy groups in the aromatic nucleus

, 2021
I. I. Gaidarzhy, L. A. Motnyak, B. V. Kunshenko   +2 more
openalex   +1 more source

Solubility and thermodynamic studies of procaine hydrochloride in propylene glycol + 2-propanol binary mixtures at different temperatures

Results in Chemistry
In the present work, the solubility of procaine-HCl was determined in propylene glycol (PG) +2-propanol mixtures at temperatures of 298.2–313.2 K. The maximum solubility of procaine-HCl in mole fraction unit was 1.84 × 10−2 in neat PG at 313.2 K and the ...
Kader Poturcu, Elaheh Rahimpour, Abolghasem Jouyban   +2 more
doaj   +1 more source

The Rare Case of a Probably True IgE-Mediated Allergy to Local Anaesthetics

Case Reports in Medicine, 2013
The majority of immediate type adverse reactions to local anaesthetics seem to be non-IgE-mediated. We report a case of a 31-year-old woman, who developed conjunctivitis and conjunctival erythema immediately after intrauterine application of a local ...
Christina Fellinger, Felix Wantke, Wolfgang Hemmer, Gabriele Sesztak-Greinecker, Stefan Wöhrl   +4 more
doaj   +1 more source