Results 61 to 70 of about 17,835 (231)

Procaine – The Controversial Geroprotector Candidate : New Insights Regarding Its Molecular and Cellular Effects

open access: yes, 2021
Since its discovery in 1905 and its employment in everyday medical practice as a local anesthetic, to its highly controversial endorsement as an “anti-aging” molecule in the sixties and seventies, procaine is part of the history of medicine and ...
Moreno-Villanueva, Maria   +4 more
core   +1 more source

Technical note on an ovine model to study biomedical implants intended for maxillofacial reconstruction

open access: yesVeterinary Surgery, EarlyView.
Abstract Objective To describe a repeated‐measures model permitting evaluation of up to four implants intended for maxillofacial applications in sheep. Animals Two‐year‐old Merino wethers (n = 5). Methods A retromandibular subparotid approach was developed through anatomical study of atlases, predissected models and cadaveric experiments.
Reza Sanaei   +7 more
wiley   +1 more source

Augmentation of peritoneal dialysis clearance with procaine

open access: yes, 1984
Augmentation of peritoneal dialysis clearance with procaine. Local anesthetic procaine in a 0.25% concentration was used as the adjunct to the dialysis fluid during peritoneal dialysis in rabbits. Procaine increased peritoneal clearance of urea (2.213 ±0.
Knapowski, Jan, Bręborowicz, Andrzej
core   +1 more source

Aromatic Amines Exert Contrasting Effects on the Anticoagulant Effect of Acetaldehyde upon APTT

open access: yesAdvances in Hematology, 2014
The pharmacological effects of amphetamine, procaine, procainamide, DOPA, isoproterenol, and atenolol upon activated partial thromboplastin time in the absence and presence of acetaldehyde have been investigated.
La'Teese Hall   +2 more
doaj   +1 more source

Local anesthetic inhibition of pancreatic phospholipase A2 action on lecithin monolayers

open access: yesJournal of Lipid Research, 1976
Using quantitative data previously reported for the penetration of local anesthetics into lecithin monolayers, the effects of surface and subphase concentrations of anesthetics on the inhibition of pancreatic phospholipase A2 action on didecanoyl ...
H S Hendrickson, M C E van Dam-Mieras
doaj   +1 more source

Effects of tempol on renal medullary tissue hypoxia in an ovine model of Gram‐negative septic acute kidney injury

open access: yesExperimental Physiology, EarlyView.
Abstract Renal arterial infusion of tempol (RAT) at the onset of Gram‐negative sepsis can prevent sepsis‐induced medullary tissue hypoxia and acute kidney injury (AKI). However, it is not known whether treatment with tempol at a clinically relevant time point of sepsis is similarly effective. Thus, we examined whether tempol can reverse renal medullary
Rachel Peiris   +10 more
wiley   +1 more source

Procaine-induced contraction in vein and its modification by drugs

open access: yes, 1969
Procaine (or lidocaine) contracted whole segments of the rhythmically contracting anterior mesenteric vein (AMV) of the cat and rat in vitro. Autonomic blocking drugs, antihistamines, and antiserotonin agents were ineffective in reducing either the ...
H. D. Sanders
core   +1 more source

Fetal glucose availability: a key regulator of the metabolic, hormonal and contractility profiles of the fetal sheep heart

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend To investigate the role of glucose availability in fetal left ventricle (LV) development, this study assessed whether maternal late gestation undernutrition (LGUN; 50% of Control diet) induced alterations in the contractility, metabolic, and hormonal profile can be ameliorated in LGUN fetuses receiving glucose infusion (LGUN+G ...
Melanie R. Bertossa   +10 more
wiley   +1 more source

STUDIES ON THE QUANTITATIVE DETERMINATION OF PROCAINE, AND SERUM PROCAINE-ESTERASE IN SURGICAL REGION Chapter III The Alteration of Procaine-Esterase Activity in Human Serum of Surgical Patients [PDF]

open access: yes, 1954
Procaine hydrochloride 0.1mg was added to the fresh serum 1ml of a surgical patient. After it was kept in an artificial incubator (37°C) for 30 minutes exactly, the amount of non-hydrolyzed procain in it was determined by the method described above.
Tanino, Jyunzo
core  

Antimicrobial prescribing guidelines for feedlot cattle

open access: yes
Australian Veterinary Journal, EarlyView.
P Cusack   +4 more
wiley   +1 more source

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