Results 1 to 10 of about 4,128 (229)
Electrochemical Detection of a Local Anesthetic Dibucaine at Arrays of Liquid|Liquid MicroInterfaces
Chemosensors, 2021 Electrochemical characterization and detection of protonated dibucaine (DIC+) at microinterface array across water|1,6-dichlorohexane were performed using cyclic voltammetry (CV) and differential pulse voltammetry (DPV).
Eissa Mohamed Almbrok +2 more
exaly +4 more sources
Solid Lipid Nanoparticles for Dibucaine Sustained Release
Pharmaceutics, 2018 Dibucaine (DBC) is among the more potent long-acting local anesthetics (LA), and it is also one of the most toxic. Over the last decades, solid lipid nanoparticles (SLN) have been developed as promising carriers for drug delivery.
Raquel De Melo Barbosa +2 more
exaly +4 more sources
Calpain Activator Dibucaine Induces Platelet Apoptosis [PDF]
International Journal of Molecular Sciences, 2011 Calcium-dependent calpains are a family of cysteine proteases that have been demonstrated to play key roles in both platelet glycoprotein Ibα shedding and platelet activation and altered calpain activity is associated with thrombotic thrombocytopenic ...
Ruichen Sun, Kesheng Dai
exaly +4 more sources
Reactions Weekly, 2020 A quinoline derivative and amino amide with anesthetic activity. Dibucaine reversibly binds to and inactivates sodium channels in the neuronal cell membrane.
semanticscholar +3 more sources
International Journal of Electrochemical Science, 2021 In this work, the electrochemical behaviour of diclofenac anion and dibucaine cation via a water|1,6-dichlorohexane liquid | liquid interface system was characterised.
E.M. Almbrok +3 more
doaj +2 more sources
Tuberculostearic Acid Controls Mycobacterial Membrane Compartmentalization [PDF]
mBio, 2023 The intracellular membrane domain (IMD) is a laterally discrete region of the mycobacterial plasma membrane, enriched in the subpolar region of the rod-shaped cell. Here, we report genome-wide transposon sequencing to discover the controllers of membrane
Malavika Prithviraj +9 more
doaj +2 more sources
Local anaesthetic systemic toxicity following oral ingestion in a child: Revisiting dibucaine
Indian Journal of Anaesthesia, 2017 Dibucaine, a potent and toxic local anaesthetic, although currently withdrawn by the United States Food and Drug Administration for use as a spinal anaesthetic, continues to remain available in many over-the-counter topical formulations.
Raylene Dias +3 more
doaj +2 more sources
Dibucaine in Ionic-Gradient Liposomes: Biophysical, Toxicological, and Activity Characterization [PDF]
Journal of Pharmacy and Science, 2018 Administration of local anesthetics is one of the most effective pain control techniques for postoperative analgesia. However, anesthetic agents easily diffuse into the injection site, limiting the time of anesthesia. One approach to prolong analgesia is
Alonso, Silvia del Valle +11 more
core +2 more sources
Dibucaine mitigates spreading depolarization in human neocortical slices and prevents acute dendritic injury in the ischemic rodent neocortex. [PDF]
PLoS ONE, 2011 Spreading depolarizations that occur in patients with malignant stroke, subarachnoid/intracranial hemorrhage, and traumatic brain injury are known to facilitate neuronal damage in metabolically compromised brain tissue.
W Christopher Risher +4 more
doaj +2 more sources
Structure Prediction and Potential Inhibitors Docking of Enterovirus 2C Proteins [PDF]
Frontiers in Microbiology, 2022 Human enterovirus infections are mostly asymptomatic and occasionally could be severe and life-threatening. The conserved non-structural 2C from enteroviruses protein is a promising target in antiviral therapies against human enteroviruses. Understanding
Daoqun Li +5 more
doaj +2 more sources