2-Butoxy-N-[2-(diethylamino)ethyl]quinoline-4-carboxamide (dibucaine)
The molecular conformation of the title compound, C20H29N3O2, is stabilized by an intramolecular C—H...O hydrogen bond. The orientation of the amide group to the ring system is characterized by a C—C—C—O dihedral ...
Bernard Van Eerdenbrugh +2 more
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Fusion of secretory vesicles isolated from rat liver [PDF]
Secretory vesicles isolated from rat liver were found to fuse after exposure to Ca2+. Vescle fusion is characterized by the occurrence of twinned vesicles with a continuous cleavage plane between two vesicles in freeze-fracture electron microscopy.
A. Amsterdam +75 more
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The penetration of local anesthetics into phosphatidylcholine monolayers
The penetration of tetracaine into monolayers of phosphatidylcholine and trioctanoin at different surface pressures, and the penetration of dibucaine, tetracaine, butacaine, lidocaine, and procaine into monolayers of didecanoylphosphatidylcholine at Π ...
H S Hendrickson
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Local anesthetic inhibition of pancreatic phospholipase A2 action on lecithin monolayers
Using quantitative data previously reported for the penetration of local anesthetics into lecithin monolayers, the effects of surface and subphase concentrations of anesthetics on the inhibition of pancreatic phospholipase A2 action on didecanoyl ...
H S Hendrickson, M C E van Dam-Mieras
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The slides are from a presentation given by Professor Ravi Iyengar from Mount Sinai School of Medicine at the Drug Forum Meeting #9 that took place in Washington, DC on February 20-21, 2008.
Ravi Iyengar
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Transient capacitance changes recorded from vestibular type I hair cells are produced by G<sub>K,L</sub> gating and do not involve neurotransmitter exocytosis. [PDF]
Abstract figure legend Schematic diagrams of mammalian wild type (WT) (A) and Caspr‐KO (B) type‐I vestibular hair cells showing localization of the Caspr protein (orange), the Ca2+ conductance (green) and the low‐voltage‐activated K+ conductance (blue).
Spaiardi P +4 more
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mutants reveal a link between deflagellation and intraflagellar transport [PDF]
Background Cilia and flagella are often lost in anticipation of mitosis or in response to stress. There are two ways that a cell can lose its flagella: resorption or deflagellation.
Jeremy David Kirk Parker +2 more
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Contact allergy to local anaesthetics–value of patch testing with a caine mix in the baseline series [PDF]
BACKGROUND: Contact allergy to local anaesthetics is relatively common. Patch testing with benzocaine in the European baseline series is recommended for diagnosis, even though a caine mix has been previously suggested to be superior.
Brinca, A +2 more
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Scratching behavior observed after epicutaneous challenge with the antigen 2,4-dinitrofluorobenzene (DNFB) in the ear of BALB/c mice passively sensitized with anti-dinitrophenol (DNP).
Keiichi Musoh +4 more
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New Insights into Butyrylcholinesterase Activity Assay: Serum Dilution Factor as a Crucial Parameter. [PDF]
Butyrylcholinesterase (BChE) activity assay and inhibitor phenotyping can help to identify patients at risk of prolonged paralysis following the administration of neuromuscular blocking agents. The assay plays an important role in clinical chemistry as a
Joanna Jońca +7 more
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