Results 51 to 60 of about 1,590 (187)
Cytoskeleton, Volume 81, Issue 11, Page 586-604, November 2024.Abstract Most cells tightly control the length of their cilia. The regulation likely involves intraflagellar transport (IFT), a bidirectional motility of multi‐subunit particles organized into trains that deliver building blocks into the organelle. In Chlamydomonas, the anterograde IFT motor kinesin‐2 consists of the motor subunits FLA8 and FLA10 and ...
Mansi B. Patel +10 more
wiley +1 more source
Potent inhibition of anoxic depolarization by the sodium channel blocker dibucaine
, 2011 Recurring waves of peri-infarct depolarizations (PIDs) propagate across gray matter in the hours and days following stroke, expanding the primary site of injury.
R. David Andrew +4 more
core +1 more source
Anti-Leishmania efecct of intralesional procaíne and dibucaíne in hamsters
Revista Científica, 2010 The effect of intralesional treatment (IL) with Procaine and Dibucaine was compared with standard dosages of Glucantime® administered intramuscularly (IM) to attain clinical and parasitological cures in skin lesions in outbred male hamsters infected ...
Dalmiro José Cazorla Perfetti +4 more
doaj
Structure and function of FAP47 in the central pair apparatus of Chlamydomonas flagella
Cytoskeleton, Volume 81, Issue 11, Page 669-680, November 2024.Abstract Motile cilia have a so‐called “9 + 2” structure, which consists of nine doublet microtubules and a central pair apparatus. The central pair apparatus (CA) is thought to interact mechanically with radial spokes and to control the flagellar beating. Recently, the components of the CA have been identified by proteomic and genomic analyses. Still,
Yuma Tani +3 more
wiley +1 more source
, 1995 Dibucaine and 8-(N,N-diethylamino)octyl 3,4,5-trimethoxybenzoate (TMB-8), which are local anesthetics, affect diverse functions of many cell types. For example, platelet aggregation is inhibited by both, and both cause changes in platelet morphology and
B. J. Druker +4 more
core +1 more source
Relaxation dynamics of amorphous dibucaine using dielectric studies [PDF]
, 2015 Using broadband dielectric spectroscopy the molecular mobility of dibucaine is investigated in the supercooled liquid and gassy states, over a wide temperature range for some test frequencies.
CAPACCIOLI, SIMONE +7 more
core +1 more source
Determination of nimodipine in plasma by HPLC-MS/MS and pharmacokinetic application
Brazilian Journal of Pharmaceutical Sciences, 2010 To develop and validate a rapid, specific and highly sensitive method to quantify nimodipine in human plasma using dibucaine as the internal standard (IS).
Demétrius Fernandes do Nascimento +11 more
doaj +1 more source
Insights into degradation and targeting of the photoreceptor channelrhodopsin‐1
Plant, Cell &Environment, Volume 47, Issue 11, Page 4188-4211, November 2024.Abstract In Chlamydomonas, the directly light‐gated, plasma membrane‐localized cation channels channelrhodopsins ChR1 and ChR2 are the primary photoreceptors for phototaxis. Their targeting and abundance is essential for optimal movement responses. However, our knowledge how Chlamydomonas achieves this is still at its infancy.
Michaela Wolfram +7 more
wiley +1 more source
Structural determination and modeling of ciliary microtubules
Acta Crystallographica Section D, Volume 80, Issue 4, Page 220-231, April 2024.This review describes how electron‐microscopy methods have helped to reveal the structure of the ciliary axoneme.The axoneme, a microtubule‐based array at the center of every cilium, has been the subject of structural investigations for decades, but only recent advances in cryo‐EM and cryo‐ET have allowed a molecular‐level interpretation of the entire ...
Travis Walton +2 more
wiley +1 more source
Characteristics of dibucaine inhibition of “usual” and “atypical” forms of BChE.
, 2015 DN values were calculated in assays performed at various dibucaine concentration at 25°C using 5mM BTC (A) or PTC (B) as substrate with two types of 400-fold diluted serum samples from heterozygous individuals with usual UU and UA phenotype.
Krzysztof Waleron (804438) +7 more
core +1 more source