Results 71 to 80 of about 4,128 (229)
Plant chemical genetics : from phenotype-based screens to synthetic biology [PDF]
, 2017 The treatment of a biological system with small molecules to specifically perturb cellular functions is commonly referred to as chemical biology. Small molecules are used commercially as drugs, herbicides, and fungicides in different systems, but in ...
Dejonghe, Wim, Russinova, Eugenia
core +3 more sources
Structure and function of FAP47 in the central pair apparatus of Chlamydomonas flagella
Cytoskeleton, Volume 81, Issue 11, Page 669-680, November 2024.Abstract Motile cilia have a so‐called “9 + 2” structure, which consists of nine doublet microtubules and a central pair apparatus. The central pair apparatus (CA) is thought to interact mechanically with radial spokes and to control the flagellar beating. Recently, the components of the CA have been identified by proteomic and genomic analyses. Still,
Yuma Tani +3 more
wiley +1 more source
CHIMIA, 1992 A comprehensive summary of basic relations for quantitative IR ATR spectroscopy of isotropie and oriented samples is given. Experimental requirements for detection of sub-monolayer quantities in aqueous environment are discussed.
Urs Peter Fringeli
doaj +2 more sources
From micro- to nanostructured implantable device for local anesthetic delivery [PDF]
, 2016 Local anesthetics block the transmission of painful stimuli to the brain by acting on ion channels of nociceptor fibers, and find application in the management of acute and chronic pain. Despite the key role they play in modern medicine, their cardio and
Allegri, Massimo +9 more
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Insights into degradation and targeting of the photoreceptor channelrhodopsin‐1
Plant, Cell &Environment, Volume 47, Issue 11, Page 4188-4211, November 2024.Abstract In Chlamydomonas, the directly light‐gated, plasma membrane‐localized cation channels channelrhodopsins ChR1 and ChR2 are the primary photoreceptors for phototaxis. Their targeting and abundance is essential for optimal movement responses. However, our knowledge how Chlamydomonas achieves this is still at its infancy.
Michaela Wolfram +7 more
wiley +1 more source
Anti-Leishmania efecct of intralesional procaíne and dibucaíne in hamsters
Revista Científica, 2010 The effect of intralesional treatment (IL) with Procaine and Dibucaine was compared with standard dosages of Glucantime® administered intramuscularly (IM) to attain clinical and parasitological cures in skin lesions in outbred male hamsters infected ...
Dalmiro José Cazorla Perfetti +4 more
doaj
Pharmacogenetics of analgesic drugs [PDF]
, 2013 • Individual variability in pain perception and differences in the efficacy of analgesic drugs are complex phenomena and are partly genetically predetermined.
Branford, R +4 more
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Structural determination and modeling of ciliary microtubules
Acta Crystallographica Section D, Volume 80, Issue 4, Page 220-231, April 2024.This review describes how electron‐microscopy methods have helped to reveal the structure of the ciliary axoneme.The axoneme, a microtubule‐based array at the center of every cilium, has been the subject of structural investigations for decades, but only recent advances in cryo‐EM and cryo‐ET have allowed a molecular‐level interpretation of the entire ...
Travis Walton +2 more
wiley +1 more source
Biotechnology and Bioengineering, Volume 121, Issue 1, Page 355-365, January 2024.This study identifies transcriptional biomarkers that can detect load stress in Escherichia coli. By analyzing RNA‐seq data collected in heterologous gene expression cases and various conditions, the authors developed an ensemble of machine learning models to identify a minimal number of biomarkers discriminating load stress states from other cellular ...
Yiming Huang, Anil Wipat, Jaume Bacardit
wiley +1 more source
Aktivnost kolinesteraza u punoj ljudskoj krvi mjerena acetiltiokolinom kao supstratom i etopropazinom kao selektivnim inhibitorom butirilkolinesteraze u plazmi [PDF]
, 2004 A procedure is suggested for measuring acetylcholinesterase and butyrylcholinesterase activities in human whole blood using acetylthiocholine as a substrate and ethopropazine as a selective inhibitor of butyrylcholinesterase.
Anita Bosak +2 more
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