Results 61 to 70 of about 1,590 (187)

Transcriptional biomarker discovery toward building a load stress reporting system for engineered Escherichia coli strains

open access: yesBiotechnology and Bioengineering, Volume 121, Issue 1, Page 355-365, January 2024.
This study identifies transcriptional biomarkers that can detect load stress in Escherichia coli. By analyzing RNA‐seq data collected in heterologous gene expression cases and various conditions, the authors developed an ensemble of machine learning models to identify a minimal number of biomarkers discriminating load stress states from other cellular ...
Yiming Huang, Anil Wipat, Jaume Bacardit
wiley   +1 more source

Metabolism of dibucaine. II. Disposition and metabolism of dibucaine in rats.

open access: yesJournal of Pharmacobio-Dynamics, 1989
The disposition and metabolism of dibucaine were studied in rats. After intraperitoneal administration of 3H-labelled dibucaine, the blood concentration of total radioactivity reached a maximum at 10 min and declined thereafter, with a biphasic curve having half-lives of 37.7 min and 11.2 h. Radioactivity in the tissues after administration was high in
IGARASHI, Kazuo   +2 more
openaire   +3 more sources

Ion-pair Spectrophotometric Determination of Dibucaine

open access: yes, 2000
A simple and sensitive spectrophotometric determination of dibucain has been established. It is based on the formation of colored ion-pair complexes between Dibucaine and each of Orange II, Orange G, Bromothymol blue and Bromocresol green.
Ali Z.Abu Zuhri   +2 more
core   +1 more source

Local anesthetics—phospholipid interaction. A study of Dibucaine binding to lipid monolayers.

open access: yes, 1988
The interactions of the local anesthetic Dibucaine with some lipid monolayers were studied at the air/water interface by measuring the surface pressure-area and the surface potential-area isotherms at different pH values of 4, 7 and 10 respectively.
Möbius, D.   +3 more
core   +1 more source

Photophysical properties of dibucaine and primaquine : a comparison study

open access: yes, 1990
The purpose of this thesis was to compare two different drugs, dibucaine and primaquine, in their photophysical properties and their interaction with bacteriorhodopsine (bR) purple membrane.
Chyan, Yann-Guang
core  

Membrane effects of trifluoperazine, dibucaine and praziquantel on human erythrocytes

open access: yes, 2000
Trifluoperazine (TFP) is a potent antipsychotic agent, dibucaine (DBC) is a local anaesthetic and praziquantel (PZQ) is a highly effective agent against schistosomiasis. The present work was conducted to (i) investigate the cytotoxic effects of TFP, DEC
Malheiros, SVP   +3 more
core   +1 more source

The effect of membrane active agents on human leukaemia cells [PDF]

open access: yes, 1998
This Thesis investigates the effect of membrane-active agents, such as synthetic ether lipids (SEL), local anaesthetics and polyunsaturated fatty acids (PUFAs) on human leukaemia cells.
Jones, Eirian Wynne
core  

A METHOD FOR THE DETECTION OF ATYPICAL FORMS OF HUMAN SERUM CHOLINESTERASE. DETERMINATION OF DIBUCAINE NUMBERS

open access: yes, 1957
Cases with atypical esterase activity were found by determining esterase inhibition in numerous sera. A suitable inhibitor was the local anaesthetic dibucaine (cinchocaine, TN Nupercaine, Perkain). A good discrimination between typical and atypical sera
K. Genest, W. Kalow
core   +1 more source

Formulation of unavailable diagnostic haptens for the detection of contact allergy to topical medications in the Polish Baseline Series

open access: yesAlergologia Polska
The necessity of routine patch testing to topical medications reflects the frequency of contact allergy to these haptens as well as their presence in many popular medicinal products. At present, Polish Baseline Series includes 7 drugs tested individually
Radosław Śpiewak   +2 more
doaj   +1 more source

Dibucaine number (DN) in duodenal ulcer

open access: yesThe American Journal of Digestive Diseases, 1977
Dibucaine Number (DN) was determined in 103 patients suffering from duodenal ulcer diagnosed radiologically and 214 normal subjects (control). Statistically significant (p less than 0.001) difference was observed in the distribution of DN in the two groups. Whereas 94% of the control subjects had normal DN (above 70), 6% had intermediate DN (between 40-
K, Ahmad, N, Anwar, A, Sattar
openaire   +3 more sources

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