Results 61 to 70 of about 4,128 (229)
Journal of Biological Chemistry, 1980 Ca2+-activated, phospholipid-dependent protein kinase recently found in mammalian tissues (Takai, Y., Kishimoto, A., Iwasa, Y., Kawahara, Y., Mori, T., and Nishizuka, Y. (1979) J. Biol. Chem.
T. Mori +4 more
semanticscholar +1 more source
Archiv der Pharmazie, Volume 358, Issue 1, January 2025.This review explores the potential of natural products in modulating tau hyperphosphorylation, a pivotal molecular mechanism in Alzheimer's disease onset, by inhibiting kinases, enhancing phosphatase activity, blocking fibril formation, and promoting its disaggregation.
Gustavo Basurto‐Islas +4 more
wiley +1 more source
Transcript expression of vesicular glutamate transporters in lumbar dorsal root ganglia and the spinal cord of mice – Effects of peripheral axotomy or hindpaw inflammation [PDF]
, 2013 Using specific riboprobes, we characterized the expression of vesicular glutamate transporter (VGLUT)1–VGLUT3 transcripts in lumbar 4–5 (L4–5) dorsal root ganglions (DRGs) and the thoracolumbar to lumbosacral spinal cord in male BALB/c mice after a 1- or
Brumovsky, Pablo Rodolfo +8 more
core +1 more source
Emerging Therapeutics in the Fight Against EV‐D68: A Review of Current Strategies
Influenza and Other Respiratory Viruses, Volume 18, Issue 12, December 2024.ABSTRACT Enterovirus‐D68 (EV‐D68) was first identified in 1962 in pediatric patients with acute respiratory conditions in California, USA (US). From the 1970s to 2005, EV‐D68 was underestimated due to limited data and serotyping methods. In 2014, the United States experienced outbreaks of acute flaccid myelitis (AFM) in children EV‐D68 positive.
Nida Kalam +1 more
wiley +1 more source
In vitro release of dibucaine hydrochloride from chitosan semisolid vehicles: emulsion and hydrophilic gels [PDF]
Journal of Pharmacy & Pharmacognosy Research, 2017 Context: Chitosan has received attention as a functional, sustainably renewable, nontoxic and biodegradable biopolymer for pharmaceutical applications.
Nilia de la Paz +6 more
doaj
Genetic control of drug metabolism and drug action in man [PDF]
, 1985 The study of genetic factors that modify the individual response to drugs, referred to as "pharmacogenetics" is relatively new field, a discipline at the interface between genetic and clinical pharmacology.
Raghupati Sarma, G
core
A Flagellar A-Kinase Anchoring Protein with Two Amphipathic Helices Forms a Structural Scaffold in the Radial Spoke Complex [PDF]
, 2012 A-kinase anchoring proteins (AKAPs) contain an amphipathic helix (AH) that binds the dimerization and docking (D/D) domain, RIIa, in cAMP-dependent protein kinase A (PKA). Many AKAPs were discovered solely based on the AH–RIIa interaction in vitro.
Alto +71 more
core +2 more sources
Cytoskeleton, Volume 81, Issue 11, Page 586-604, November 2024.Abstract Most cells tightly control the length of their cilia. The regulation likely involves intraflagellar transport (IFT), a bidirectional motility of multi‐subunit particles organized into trains that deliver building blocks into the organelle. In Chlamydomonas, the anterograde IFT motor kinesin‐2 consists of the motor subunits FLA8 and FLA10 and ...
Mansi B. Patel +10 more
wiley +1 more source
, 2016 Retrospective studies indicate that the use of regional anesthesia can reduce cancer recurrence after surgery which could be due to ranging from immune function preservation to direct molecular mechanisms.
Chen, L +5 more
core +3 more sources