Results 121 to 130 of about 683,469 (288)

DNA and Due Process [PDF]

open access: yes, 2010
The U.S. Supreme Court in District Attorney\u27s Office v. Osborne confronted novel and complex constitutional questions regarding the postconviction protections offered to potentially innocent convicts. Two decades after DNA testing exonerated the first
Garrett, Brandon L.
core   +2 more sources

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

open access: yesMolecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski   +9 more
wiley   +1 more source

Judicial Errors and Crime Deterrence: Theory and Experimental Evidence [PDF]

open access: yes
The standard economic theory of crime deterrence predicts that the conviction of an innocent (type-I error) is as detrimental to deterrence as the acquittal of a guilty individual (type-II error).
Luca Stanca, Matteo Rizzolli
core  

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Practical Aspects of an Activity of Concerned Persons at Realization of Court Decisions About Imposition/cancelation of Property Arrest in Civil Procedure [PDF]

open access: yes, 2017
The analysis of practical aspects of decisions of a court, executive office, public registers at securing a claim as an arrest of probable debtor\u27s property and/or cancelation of it is carried out in the article.
Marchenko, H. (Halyna)
core  

Decision procedures for linear arithmetic

open access: yes, 2019
Nous introduisons dans cette thèse quelques procédures de décision nouvelles pour l'arithmétique linéaire adaptées à une utilisation dans le cadre de la résolution de contraintes modulo théories (SMT) ou d'outils de déduction automatique.1) CutSat++ est un calcul pour l'arithmétique linéaire sur les entiers qui intègre des techniques issues de la ...
openaire   +2 more sources

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Moody Choice [PDF]

open access: yes
If choices depend on the decision maker's mood, is the attempt to derive any consistency in choice doomed? In this paper we argue that, even with full unpredictability of mood, the way choices from a menu relate to choices from another menu exhibits some
Manzini, Paola, Mariotti, Marco
core  

Legitimacy and procedural justice in prisons [PDF]

open access: yes, 2010
All social situations are ‘ordered’ in some way, comprising a constantly changing set of relationships that establish the structure within which human action occurs.
Bradford, Ben   +4 more
core  

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