ALDOA Promotes Glycolysis and NLRP3/GSDMD Pyroptosis to Accelerate ALS Progression
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is characterized by progressive motor neuron degeneration. Glycolytic dysregulation is implicated in disease progression, yet the underlying mechanisms remain unclear. This study investigates how Aldolase A (ALDOA) drives ALS progression through glycolysis‐mediated motor neuron pyroptosis.
Kaixin Yan +9 more
wiley +1 more source
Psychological features of dispute content and public acceptance of AI in legal adjudication: evidence for systematic variation beyond individual differences. [PDF]
Fujita M, Watamura E.
europepmc +1 more source
ABSTRACT Objective Stereoelectroencephalography‐guided radiofrequency thermocoagulation (SEEG‐RFTC) has emerged as a safe and effective minimally invasive treatment for children with drug‐resistant focal epilepsy. Although evidence from real‐world studies remains limited, numerous pediatric cases have demonstrated promising outcomes. This retrospective
Weitao Chen +7 more
wiley +1 more source
Minimum caseload for cost-effective robotic-assisted surgery: a systematic review. [PDF]
Garavini AB +9 more
europepmc +1 more source
Coronary Revascularization in the Era of TAVR: Timing, Strategy, and Outcomes. [PDF]
Love A, O'Leary C, Shahab S.
europepmc +1 more source
Approximation and mutual recognition of procedural safeguards of suspects and defendants in criminal proceedings throughout the European Union’ [PDF]
van Puyenbroeck, Laurens +1 more
core +1 more source
Reconsidering Carotid Artery Stenting for Asymptomatic Carotid Stenosis in the Era of Endovascular Evolution. [PDF]
DeYoung C, Lucke-Wold B.
europepmc +1 more source
Pre-procedural left atrial strain and clinical features for predicting recurrence after first catheter ablation of persistent atrial fibrillation: a prospective cohort study. [PDF]
Tu Q, Xiao D.
europepmc +1 more source
Veno-Venous Extracorporeal Membrane Oxygenation for High-Risk Airway Interventions: A Safety-Net Hospital Case Series. [PDF]
Rothweiler S +3 more
europepmc +1 more source

