Results 91 to 100 of about 4,901,630 (319)
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
PR-2 DEP Special Consideration Procedure
, 2013 A Disability Equipment Program procedure covering special considerations. The target audience is approved prescribers and Aged and Disability Program Staff.
Department of Health
core
, 2013 After the official publishing of 2009/128/CE Directive, the Spanish Ministry of Agriculture, Food and Environment started to develop the national law (Real Decreto) to implement the EU mandate, specifically for those aspects concerning Article 8.
Montemayor, V., Gil, E., Gracia, F.
core +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Obligations in classical procedure [PDF]
, 2008 The civil law gave the praetor relatively few rules of procedure with which to manage a tribunal. Accordingly many rules of procedure were the product of the praetor's own active lawmaking.
Metzger, E.
core
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
PR-1 DEP Application and Eligibility Procedure
, 2013 A Disability Equipment Program procedure covering application and eligibility to the program. The target audience is approved prescribers and Aged and Disability Program Staff.
Department of Health
core
ID3.5 - Intake Procedure [PDF]
, 2007 The document describes the procedure which WP3 will follow when an Aspect Work Package offers a component for integration in the TENCompetence system.The work on this publication has been sponsored by the TENCompetence Integrated Project that is funded ...
Lemmers, Ruud
core