Results 111 to 120 of about 4,901,630 (319)
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Proposal for a New Norwegian Code of Criminal Procedure - A Summary of NOU 2016: 24
The Committee of Criminal Procedure
doaj +1 more source
OBLIGATIONS TO ACQUIRE OR PRESERVE PROPERTY WITHOUT SUFFICIENT LEGAL BASIS
The article deals with theoretical and practical issues concerning obligations to acquire and preserve property without sufficient legal grounds.
Iryna Veres, Yurii Yurkevych
doaj +1 more source
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Diversity and complexity in neural organoids
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
The right of access to official information is really important. The constitution of RK fixes guarantees of realization of the right of citizens to information, based on the fact that the right to information is a fundamental human right.
S. Tynybekov., R. Erezhepkyzy.
doaj
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Rehabilitation after Latarjet Procedure
Background and Purpose: Anterior dislocation is one of the more common injuries affecting the shoulder. There are relatively high rates of developing recurrent anterior instability, particularly among young males.
Vigil, Nathan
core
Optimizing Outcome of Charles Procedure for Chronic Lower Extremity Lymphoedema
Background: The Charles procedure for late-stage lower limb lymphoedema ( LLL) is often criticized for its unpredictable and poor results. We have adopted a systematic approach to optimize outcome of patients treated with this excisional surgery. Methods:
Karri, Vasu; Yang, Ming-Chin; Lee, Il Jae; Chen, Shih-Heng; Hong, Joon Pio; Xu, Enny-Sonia; Cruz-Vargas, Jaqueline; Chen, Hung-Chi +1 more
core +1 more source
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source

