Results 151 to 160 of about 5,635,335 (262)

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

L'attività scientifica subacquea - Procedure operative ed esigenze di sicurezza

, 2014
Le immersioni subacquee sono attività di primario interesse in vari ambiti della ricerca scientifica. Il loro svolgimento comporta rischi per gli operatori che vanno minimizzati attraverso un'attenta e adeguata programmazione e l'adozione di misure e ...
Gianluca Sotis, Claudio Barchesi, Michele Sciarra, Mirko Passera   +3 more
core  

Real-World Applicability of Multiple International Terminology Systems in Oncology: Mapping Study of Clinical Terms for Cancer Diagnosis and Treatment. [PDF]

JMIR Med Inform
Jang B, Park E, Lee S, Ju E, Jang Y, Kwak IH, Choi KS, Kong HJ, Cha HS, Kim HJ, Chae H.   +10 more
europepmc   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Endoscopic management of buried bumper syndrome in children using a dedicated endoscopic resection device (Flamingo): A single-centre retrospective case series. [PDF]

JPGN Rep
Adima A, Patel Y.
europepmc   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Environmental Impact of Conventional Versus Underwater Endoscopic Mucosal Resection for Colorectal Lesions: A Procedure-Based Life Cycle Assessment With Pooled Effectiveness Estimates. [PDF]

DEN Open
Calabrese G, Moll F, Neves JAC, Bonacci L, Sinagra E, Castiglione F, Maida M, Albéniz-Arbizu E, Pioche M, Sferrazza S.   +9 more
europepmc   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Determinazioni dei tributi e procedure concorsuali

, 2017
si tratta della curatela del volume aspetti fiscali delle procedure concorsuali e della redazione diretta di 6 paragrafi per complessive 16 pagine circa.
Lupi, R
core  

Outcomes and Complications of Monobloc Versus Le Fort III Procedures for Treating Craniosynostosis: A Literature Review. [PDF]

Plast Reconstr Surg Glob Open
Chamma B, Nagappala S, Arnold M, Trumza S, Samir Tadrousse K, Kapur S, Houdi M, Simman R.   +7 more
europepmc   +1 more source