Results 171 to 180 of about 11,159,071 (355)
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Dental Surgeries in Hospitals and Surgery Centers for Children With Developmental Disabilities. [PDF]
Rancaño KM +5 more
europepmc +1 more source
Westinghouse Astronuclear Experimental Facility criticality hazards control procedure
USDOE National Nuclear Security Administration (NNSA), Nuclear Criticality Safety Program (NCSP) +1 more
openalex +2 more sources
Automated long-term measurement of swallowing as a new procedure in dysphagia diagnostics
V Segler +7 more
openalex +1 more source
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Efficacy and Safety of Repeated Radiofrequency Thermocoagulation on Trigeminal Neuralgia Patients. [PDF]
Luikku AJ +8 more
europepmc +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Update--Criminal Law & Procedure [PDF]
Berner, Bruce G., Vandercoy, David E.
core +1 more source

