Results 111 to 120 of about 5,909,358 (337)
Molecular Oncology, EarlyView.This study investigates gene expression differences between two major pediatric acute lymphoblastic leukemia (ALL) subtypes, B‐cell precursor ALL, and T‐cell ALL, using a data‐driven approach consisting of biostatistics and machine learning methods. Following analysis of a discovery dataset, we find a set of 14 expression markers differentiating the ...
Mona Nourbakhsh +8 more
wiley +1 more source
Establishment of specialist commercial courts in the State of Qatar: A comparative study
International Review of Law, 2016 The social and economic progress witnessed in Qatar, similar to other countries in the world, has led to the emergence of commercial transactions that were not previously known, thus the need for establishing specialist commercial courts to address ...
Mohammed Abdulaziz Al-Khulaifi +1 more
doaj +2 more sources
8th North American Caribou Workshop, 20-24 April 1998, Whitehorse, Yukon, Canada.
Rangifer, 2000 Two hundred and forty people attended the 8th North American Caribou Workshop. Attendees brought perspectives from government and private sector research, management, industry, boards, councils and First Nations.
R.E. Haugerud (ed. in chief) +1 more
doaj +1 more source
Color superconductivity and the strange quark
, 2005 At ultra-high density, matter is expected to form a degenerate Fermi gas of quarks in which there is a condensate of Cooper pairs of quarks near the Fermi surface: color superconductivity. In these proceedings I review some of the underlying physics, and
Alford, Mark G
core +2 more sources
Molecular Oncology, EarlyView.mir‐196a promotes Esophagus Adenocarcinoma aggressiveness. On one hand, mir‐196a targets the valosin‐containing protein (VCP) mRNA, causing the accumulation of c‐MYC protein that leads to high amounts of TERT. On the other hand, mir‐196a targets the inhibitor of NFκB (NFKBIA).
Jesús García‐Castillo +8 more
wiley +1 more source
Proceedings of Local Branches, Society of American Bacteriologists (Washington, Eastern Pennsylvania, Michigan) [PDF]
, 1947 M S SHORB
openalex +1 more source
Genomics‐led approach to drug testing in models of undifferentiated pleomorphic sarcoma
Molecular Oncology, EarlyView.GA text Genomic data from undifferentiated pleomorphic sarcoma patients and preclinical models were used to inform a targeted drug screen. Selected compounds were tested in 2D and 3D cultures of UPS cell lines. A combination of trametinib and infigratinib was synergistic in the majority of UPS cell lines tested, which was further confirmed in an ex ...
Piotr J. Manasterski +19 more
wiley +1 more source
A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner
Molecular Oncology, EarlyView.We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp +13 more
wiley +1 more source