Results 141 to 150 of about 6,083,333 (340)
Linear and nonlinear coupling of quantum dots in microcavities
, 2010 We discuss the topical and fundamental problem of strong-coupling between a quantum dot an the single mode of a microcavity. We report seminal quantitative descriptions of experimental data, both in the linear and in the nonlinear regimes, based on a ...
Cancellieri, E. +5 more
core
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
Proceedings of the 2023 IEEE 32nd Asian Test Symposium ATS 2023 [PDF]
, 2023 openalex +1 more source
Nucleon Spin Structure and Parton Distribution Functions
, 2011 This article gives an overview over recent results on quark and gluon helicity distributions obtained in deep inelastic lepton nucleon scattering and proton proton interactions.
Pretz, Joerg
core
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Molecular Oncology, EarlyView.Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
(P.) Funke and (M.) Haake Eds. Greek Federal States and their Sanctuaries: Identity and Integration. Proceedings of an International Conference of the Cluster of Excellence ‘Religion and Politics’ Held in Münster, 17.06. – 19.06.2010. Stuttgart: Franz Steiner Verlag, 2013. Pp. 244. €52. 9783515103077. [PDF]
, 2015 Erica Angliker
openalex +1 more source
Molecular Oncology, EarlyView.Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad +12 more
wiley +1 more source
Molecular Oncology, EarlyView.We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck +12 more
wiley +1 more source