Results 131 to 140 of about 17,633,707 (261)
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Discerning protein pools by selective staining with self‐labeling tags
FEBS Letters, EarlyView.Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley +1 more source
FEBS Letters, EarlyView.Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
PROCESS OF MANAGEMENT OF VALUES IN SYSTEM OF FUNCTIONING OF companies
Вестник университета, 2016 Exactly today, when the set of the companies should fight for the segment, the product, service or even idea in the concrete market, high degree of relevance are got by a problem of influence of social methods of management on financial and economic ...
I. Musaelyan
doaj
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Acta Scientiarum: Language and Culture, 2009 O artigo está apoiado no contexto atual das dificuldades de desenvolvimento da competência de leitura, situa-se na intersecção pesquisa/ensino e é orientado pelos estudos psicolinguísticos sobre predição leitora.
Vera Wannmacher Pereira
doaj
Sussman/prejza & Company: Beyond Graphic Design
, 1995 p 142; ill.; bibl.; 30 ...
PROCESS ARCHITECTURE 124
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