Results 141 to 150 of about 17,633,707 (261)

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Epigenetic reprogramming of lineage switching in cancer

open access: yesFEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı   +4 more
wiley   +1 more source

Understanding Variation and Statistical Process Control: Variation and Process Capability Calculations

open access: yes, 2017
This video, published by the Nanotechnology Applications and Career Knowledge Support (NACK) Center at Pennsylvania State University, focuses on variation and process capability calculations.
Johnson, Lou (process engineer)
core   +1 more source

Co-Designing Wellbeing Initiatives With Rural Adolescents: What Works, What Doesn't, and Why. [PDF]

open access: yesHealth Promot J Austr
Kernot J   +7 more
europepmc   +1 more source

Architectural Institute Of Japan Design Prize 1994

open access: yes, 1995
p 127; ill.; bibl.; 30 ...
PROCESS ARCHITECTURE 125
core  

The microbiome in human skin aging

open access: yesFEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana   +3 more
wiley   +1 more source

ReFraming The FaPMI (Families Where a Parent Has a Mental Illness) Program: Using a Participatory Action Research Approach to Create Change. [PDF]

open access: yesInt J Ment Health Nurs
Allchin B   +29 more
europepmc   +1 more source

Home - About - Disclaimer - Privacy