Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Exploring the occupational therapy goal-setting process with immigrant families of children with disabilities in the Australian context. [PDF]
Fenn SN, Jojo N, Isbel S, Pearce C.
europepmc +1 more source
Liver organoids: modelling complexity in homeostasis and disease
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
A Qualitative Study on Mothers' Experiences of Breastfeeding Cessation in Turkey. [PDF]
Hur S, Solt Kirca A, Avcı Başboğa N.
europepmc +1 more source
Epigenetic reprogramming of lineage switching in cancer
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
This video, published by the Nanotechnology Applications and Career Knowledge Support (NACK) Center at Pennsylvania State University, focuses on variation and process capability calculations.
Johnson, Lou (process engineer)
core +1 more source
Co-Designing Wellbeing Initiatives With Rural Adolescents: What Works, What Doesn't, and Why. [PDF]
Kernot J +7 more
europepmc +1 more source
Architectural Institute Of Japan Design Prize 1994
p 127; ill.; bibl.; 30 ...
PROCESS ARCHITECTURE 125
core
The microbiome in human skin aging
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source
ReFraming The FaPMI (Families Where a Parent Has a Mental Illness) Program: Using a Participatory Action Research Approach to Create Change. [PDF]
Allchin B +29 more
europepmc +1 more source

