Results 81 to 90 of about 6,729,806 (248)

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

Atomic-scale chemical mechanical polishing: advances and challenges for the post-Moore’s law era

open access: yesMaterials Futures
Chemical mechanical polishing (CMP) has emerged as a critical technology for local and global surface planarization in integrated circuit manufacturing for decades.
Lifei Zhang, Xinchun Lu
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Algorithm for designing domestic wastewater treatment process flow based on BP-SVM

open access: yesXi'an Gongcheng Daxue xuebao
In order to improve the efficiency of domestic wastewater treatment process design, a wastewater treatment process database was established to save data samples abstracted from real domestic wastewater treatment processes, and the process was selected by
ZHANG Jianmin, CHEN Minjie
doaj   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

The Process for the Design, Development, and Implementation of Small Private Online Course (SPOC)

open access: yesEducational Process: International Journal
Background/purpose. This study examines the design, development, and implementation of Small Private Online Courses (SPOCs) at Bulacan State University to standardize high-quality instructional materials and support asynchronous online learning ...
Joseline Santos   +2 more
doaj   +1 more source

Establishmentofevaluationindexsystemofpatientsafetymanagementinoperatingroom

open access: yesHuli yanjiu, 2018
Objective:Todevelopevaluationindexsystemofpatientsafetymanagementinoperatingroom,inordertoreducehiddendangerofpatientsafety,effectivelypreventsafetyaccidents.Methods:Adverseeventsassociatedwithsurgerypatientsafetymanagement ...
TanLiying
doaj  

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Application of HFMEA in management of transfusion during hospital transport for emergency patients

open access: yesHuli yanjiu, 2018
Objective:To improve the quality of transfusion during hospital transport in emergency patients and ensure safe hospital transport for emergency patients.Methods:Healthcare failure mode and effect analysis(HFMEA)were used, management flow chart for ...
阳佩, 童宇平, 张欢
doaj  

Community Participation on Flood-Prone Areas in Torue Village using Analytical Hierarchy Process

open access: yesJurnal Pendidikan Geografi Undiksha
This study examines community participation in flood disaster preparedness in Torue Village, utilizing the Analytical Hierarchy Process (AHP) to assess stakeholder contributions.
Moh Zainal   +3 more
doaj   +1 more source

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