Results 31 to 40 of about 1,889,013 (289)

Application of a high-throughput process analytical technology metabolomics pipeline to Port wine forced ageing process [PDF]

, 2014
Metabolomics aims at gathering the maximum amount of metabolic information for a total interpretation of biological systems. A process analytical technology pipeline, combining gas chromatography–mass spectrometry data preprocessing with multivariate ...
Castro, C. C., Ferreira, António C., Martins, Rui C., Teixeira, J. A.   +3 more
core   +1 more source

Platinum Clusters Anchored Amorphous NiMo Hydroxide with Collaborative Electronic Transfer for Overall Water Splitting under High Current Density

Advanced Materials Interfaces, 2022
The development of efficient and stable bifunctional catalysts to meet overall water splitting at high current densities is attractive, but also challenging.
Xinyi Zhang, Yi Han, Wenwen Cai, Dan Zhang, Zuochao Wang, Hongdong Li, Yuyao Sun, Yanyun Zhang, Jianping Lai, Lei Wang   +9 more
doaj   +1 more source

Automated processing of whole blood samples for the determination of immunosuppressants by liquid chromatography tandem-mass spectrometry [PDF]

, 2006
Background: Liquid chromatography tandem-mass spectrometry (LC-MS/MS) is an efficient technology for routine determination of immunosuppressants in whole blood; however, time-consuming manual sample preparation remains a significant limitation of this ...
Spöhrer, Ute, Vogeser, Michael
core   +1 more source

Smart sensors for process analytical technology

2016 IEEE International Conference on Advanced Intelligent Mechatronics (AIM), 2016
Increased globalisation and competition are drivers for process analytical technologies (PAT) that enable seamless process control, greater flexibility and cost efficiency in the process industries. This research is carried out in collaboration with a project which aims to introduce an integrated process control approach, embedding novel sensors for ...
Niall O' Mahony, Trevor Murphy, Krishna Panduru, Daniel Riordan, Joseph Walsh   +4 more
openaire   +3 more sources

Towards an analytical framework of science communication models [PDF]

, 2008
This chapter reviews the discussion in science communication circles of models for public communication of science and technology (PCST). It questions the claim that there has been a large-scale shift from a ‘deficit model’ of communication to a ...
A Giddens, A Gross, B Brecht, B Durodié, B Trench, B Wynne, B Wynne, D McQuail, E Einsiedel, E Einsiedel, HP Peters, J Grunig, J Rosen, J Wilsdon, J Wilsdon, J Ziman, JD Peters, K Stoker, L Hanssen, M Gibbons, M Gibbons, M Harney, M Van Sanden, P Sturgis, P. Sandman, R Dawkins, R Jackson, RG Lee, S Jasanoff, S Miller, Technology Foresight Ireland, TW Burns, U Beck, Wellcome Trust   +33 more
core   +1 more source

Ultrafine CoPt3 nanoparticles encapsulated in nitrogen‐doped carbon nanospheres for efficient water electrolysis

Electrochemical Science Advances, 2022
Rational design of nanostructures with excellent activity and stability for hydrogen evolution reaction (HER) and oxygen evolution reaction (OER) to realize efficient hydrogen production is essential for renewable energy development and conversion. Here,
Junlu Bi, Xuejun Zhai, Jingqi Chi, Xueke Wu, Shaojin Chen, Xinping Wang, Lei Wang   +6 more
doaj   +1 more source

Integrated SegFlow, µSIA, and UPLC for Online Sialic Acid Quantitation of Glycoproteins Directly from Bioreactors

Engineering in Life Sciences
This study emphasizes the critical importance of closely monitoring and controlling the sialic acid content in therapeutic glycoproteins, including EPO, interferon‐γ, Orencia, Enbrel, and others, as the level of sialylation directly impacts their ...
Letha Chemmalil, Tanmay Kulkarni, Mathura Raman, Priya Singh, Yueming Qian, Chris Chumsae, Kyle McHugh, Zhuangrong Huang, Eric Hodgman, Michael C. Borys, Julia Ding, Gloria Li, Anthony Leone   +12 more
doaj   +1 more source

Exploiting Fluorescent Reporter Molecules for Process Analytical Technology (PAT)

CHIMIA, 2009
Process Analytical Technology (PAT) launched by the U.S. Food and Drug Administration (FDA) aims to ensure the quality of pharmaceutical products. One important tool to obtain a deeper process understanding is the use of modern real-time process
Tobias Broger, Res P. Odermatt, Pablo Ledergerber, Bernhard Sonnleitner   +3 more
doaj   +1 more source

Personalized Selumetinib Dosing in Pediatric Neurofibromatosis Type 1: Insights From a Pilot Therapeutic Drug Monitoring Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate selumetinib exposure using therapeutic drug monitoring (TDM) in pediatric patients with neurofibromatosis type 1 (NF1) and plexiform neurofibromas (PN), assess interpatient pharmacokinetic variability, and explore the relationship between drug exposure, clinical response, and adverse effects.
Janka Kovács, Zoltán Köllő, Balázs Gellért Karvaly, Mahmoud Obeidat, Rita Nagy, Péter Hegyi, Brigitta Teutsch, Eszter Tuboly, Miklós Garami   +8 more
wiley   +1 more source

The Influence of Wet Granulation Parameters on the Compaction Behavior and Tablet Strength of a Hydralazine Powder Mixture

Pharmaceutics, 2023
The aim of this paper was to describe the influence of high-shear wet granulation process parameters on tablet tensile strength and compaction behavior of a powder mixture and granules containing hydralazine.
Oliver Macho, Ľudmila Gabrišová, Adam Guštafík, Kristian Jezso, Martin Juriga, Juraj Kabát, Jaroslav Blaško   +6 more
doaj   +1 more source