Results 81 to 90 of about 1,873,269 (259)

WCA Framework [PDF]

open access: yes
This article describes subject-matter and components of WCA Framework. Authors describe individual elements of WCA. Article is being coupled with explaining of WCA Framework.
Rain, Tomas, Svarcova, Ivana
core   +1 more source

Power Users and Patchworking – an Analytical Approach to Critical Studies of Young People’s Learning with Digital Media [PDF]

open access: yes, 2008
This paper sets out to problematize generational categories such as ‘Power Users’ or ‘New Millennium Learners’ by discussing these in the light of recent research on youth and ICT.
Dirckinck-Holmfeld, Lone, Ryberg, Thomas
core   +2 more sources

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

open access: yesMolecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang   +8 more
wiley   +1 more source

Seasonal Variation and Sources of Elements in Urban Submicron and Fine Aerosol in Brno, Czech Republic

open access: yesAerosol and Air Quality Research, 2020
Seasonal variation and sources of elements bound to urban aerosol were studied. Fine (PM2.5) and submicron (PM1) aerosol was collected at 2-week campaigns during four seasons in 2018.
Hana Cigánková   +5 more
doaj   +1 more source

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard   +5 more
wiley   +1 more source

Phytoremediation for heavy metal‐contaminated soils combined with bioenergy production

open access: yesJournal of Environmental Engineering and Landscape Management, 2007
In June 2007, a project started in Flanders (Belgium) in which we will apply phytoremediation to clean soils that are diffusely polluted with heavy metals.
Luc Van Ginneken   +8 more
doaj   +1 more source

Theorization and translation in information technology institutionalization: evidence from Danish home care [PDF]

open access: yes, 2014
Although institutional theory has become a more dominant perspective in information systems research, studies have only paid scant attention to how field dynamics and organizational processes coevolve during information technology institutionalization ...
Mathiassen, Lars   +2 more
core   +2 more sources

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

open access: yesMolecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed   +10 more
wiley   +1 more source

Effect of particle size distribution on spatially and angularly resolved diffuse reflectance measurement [PDF]

open access: yes, 2018
Particle size distribution is vitally important in pharmaceutical formulation. Spectroscopy is the most prominent method for in-line particle measurements and process analytics, and near-infrared (NIR) spectroscopy can be seen as the workhorse in the ...
Chen, Yi-Chieh   +5 more
core  

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

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