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Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Understanding physical exercise among individuals with substance use disorders using an integrated theoretical perspective of the health action process approach and theory of planned behavior. [PDF]
Meng Y +11 more
europepmc +1 more source
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Approaching Process Improvement
SSRN Electronic Journal, 2020Process improvement begins with the process view: understanding patient care from the patient's point of view. Organizations must also clearly articulate for themselves how they define operational excellence so that the tradeoffs taken in process improvement can be clearly made. Constructing a process map allows application of powerful analytical tools,
Itai, Gurvich +2 more
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The information-processing approach
Psychological Research, 1990The information-processing (IP) approach to perception and cognition arose as a reaction to behaviourism. This reaction mainly concerned the nature of explanation in scientific psychology. The "standard" account of behaviour, phrased in strictly external terms, was replaced by a "realist" account, phrased in terms of internal entities and processes. An
A H, van der Heijden, S, Stebbins
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A systemic approach to process modeling
Journal of Systems Integration, 1991This article presents a system’s view of a common sense management model for systems (COSMOS) [1]. Salient features of COSMOS are introduced through the unfolding story of process development of a hypothetical corporation called IM Co. This systemic view models the dynamic complexity of a system or organization so that inerrelationships, rather than ...
Raymond T. Yeh +2 more
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A Microprogrammed Approach to Signal Processing
IEEE Transactions on Computers, 1974This paper provides a summary of the design features of a microprogram controlled high speed signal processor referred to as an analyzer unit (AU). It provides an overview of the interrelationship between processing requirements, a language structure in which these requirements can be efficiently programmed, and an AU design that can efficiently ...
G. L. Kratz +2 more
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Process modeling by process owners: A decentralized approach
Software Process: Improvement and Practice, 2007AbstractMajority of current methods for process modeling utilize a centralized approach in which a group of experts work with the agents to understand, model, and improve the organization's processes. This article proposes a novel approach for process modeling that is based on the idea that modeling organizations' processes can be performed by process ...
Oktay Türetken, Onur Demirörs
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An Approach for Decentralized Process Modeling
2007This paper describes a method for organizations to perform process modeling in a decentralized and concurrent manner. The approach is based on the idea that modeling organizations' processes can be performed by individuals actually performing the processes.
Oktay Türetken, Onur Demirörs
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A Point Process Approach to Filtered Processes
Methodology And Computing In Applied Probability, 2004Let us start with a definition of a filtered process. Let \(\lambda\) be a nonnegative \(\sigma\)-finite measure on the real axis \(\mathbb R\) and \(\mu\) be a probability measure on \(\mathbb R_+\). Let \(\mathbb P\) be a Poisson point process on \(\mathbb R\times\mathbb R\) of intensity measure \(\lambda \otimes \mu\), and \(h: \mathbb R^2\times ...
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