Results 51 to 60 of about 126,259 (267)

Effect of loose abrasive mixed electrolyte on the aspect ratio of blind holes drilled in soda-lime glass by ECDM process

Manufacturing Review, 2020
Electro-Chemical Discharge Machining (ECDM) process has the potential to machine various features and 3D surfaces on glass. However, machining of high aspect ratio micro holes is a challenging problem in ECDM process.
Vemula Vijaya Vani, Chak Sanjay Kumar
doaj   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

Optimal Control Method of Parabolic Partial Differential Equations and Its Application to Heat Transfer Model in Continuous Cast Secondary Cooling Zone

Advances in Mathematical Physics, 2015
Our work is devoted to a class of optimal control problems of parabolic partial differential equations. Because of the partial differential equations constraints, it is rather difficult to solve the optimization problem. The gradient of the cost function
Yuan Wang, Xiaochuan Luo, Sai Li
doaj   +1 more source

Development of an Earthworm-Based Intestinal Soft Robot Equipped with a Gripper

Machines, 2022
An endoscopy is a tool that is used to examine the interior of a hollow organ or cavity of the body by inserting directly into the organ. However, intestinal endoscopy is not friendly to patients due to discomfort, and it can easily cause intestinal ...
Gongxin Li, Wei Qiu, Hao Wen, Mindong Wang, Fei Liu   +4 more
doaj   +1 more source

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach, Gizem Abaci, Tom Huberty, Axel Lechner, Lukas Käsmann, Jens Ricke, Sophia Stöcklein, Martin Canis, Philipp Baumeister, Marianna Alunni‐Fabbroni   +9 more
wiley   +1 more source

Automating HR Processes with Robotic Process Automation (RPA)

Journal of Engineering and Applied Sciences Technology, 2023
The integration of Robotic Process Automation (RPA) into Human Resources (HR) functions represents a significant advancement in organizational efficiency and effectiveness. RPA technology automates repetitive and rule-based tasks, allowing HR professionals to focus on strategic initiatives that add value to the organization.
openaire   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

Molecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche, Niels J. van Ruitenbeek, Charlotte Adang, Luke O'Gorman, Pui Yuen Lee, Willemijn M. Klein, Adriana C. H. van Engen‐van Grunsven, Jack A. Schalken, Sander Bervoets, Gerald W. Verhaegh, Carla M. L. van Herpen   +10 more
wiley   +1 more source

Design of a Surface Plasmon Resonance Temperature Sensor with Multi-Wavebands Based on Conjoined-Tubular Anti-Resonance Fiber

Photonics, 2021
In this work, a surface plasmon resonance (SPR) temperature sensor based on a con-joined-tubular anti-resonance optical fiber (CTF) was theoretically designed and analyzed using the finite element method.
Qiming Wang, Xuenan Zhang, Xin Yan, Fang Wang, Tonglei Cheng   +4 more
doaj   +1 more source

Extracellular vesicle lipidomics liquid biopsy reveals systemic and tumor microenvironment metabolic reprogramming in ovarian cancer

Molecular Oncology, EarlyView.
Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani, Dominic Guanzon, Andrew Lai, Katherin Scholz‐Romero, Sarah Reed, Edita Ritmejeryte, Rohan Lourie, Naven Chetty, Kaltin Ferguson, Carlos Salomon   +9 more
wiley   +1 more source

Rolling Bearing Fault Diagnosis Based on SABO–VMD–IBES–SVM

Shock and Vibration
In order to enhance the diagnostic accuracy and model generalization capability for rolling bearing faults, this paper proposes a fault diagnosis method based on an improved bald eagle search (IBES) algorithm, which is optimized using multiple strategies
Mingjing Liu, Weiyan Tong, Yingshun Li
doaj   +1 more source