Results 41 to 50 of about 712,148 (304)

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

The Phenomenon of Loss of Energy Flux Density in Pneumatic and Electromagnetic Generators for EPAT Therapy

Applied Sciences, 2022
Shock wave therapy involves introducing an acoustic wave into the living organism, whose pro-healing effect promotes the decomposition of stones and calcareous deposits. To generate such a wave, devices converting electrical energy into shock wave energy
Michał Sawicki, Michał Maćkowski, Marek Płaczek   +2 more
doaj   +1 more source

Monitoring of circulating tumor DNA allows early detection of disease relapse in patients with operable breast cancer

Molecular Oncology, EarlyView.
Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad, Marie Austdal, Oddmund Nordgård, Gunnar Mellgren, Satu Oltedal, Marie L. Austbø, Ylva H. Vignes, Thomas Helland, Kristin Jonsdottir, Tone H. Lende, Emilius A. M. Janssen, Bjørnar Gilje, Kjersti Tjensvoll, PBCB study group, Gunnar Mellgren, Tone Hoel Lende, Anette Heie, Kristin Viste, Anita Røyneberg Alvheim, Emiel AM Janssen, Kristin Jonsdottir, Ann Cathrine Kroksveen, Thomas Helland, Einar Gudlaugsson, Oddmund Nordgård, Satu Oltedal, Kristin Løge Aanestad, Jan Terje Kvaløy, Kirsten Lode, Kari Britt Hagen, Marie Austdal, Ylva H. Vignes, Siri Tungland Sola, Nina Egeland Amundsen, Finn Magnus Eliassen, Emeritus Ernst A Lien   +35 more
wiley   +1 more source

Design of Distributed Control and Emergency Shutdown System for Urea and Ammonia Plant

MATEC Web of Conferences, 2018
In modern process industries, the need for automation has become necessary to improve the feasibility of production. Automation reduces the possibility of human error and also ensures accuracy of output.
Borikar Radha Ravindra, Monica Subashini M.   +1 more
doaj   +1 more source

Simple network management protocol co- existence with hydrocarbon process automation communication real-time network [PDF]

, 2009
Hydrocarbon Process Automation Applications (HPAA) utilizes Real-time network connecting process instrumentations, controllers, and real-time logic control applications.
Almadi, S, El-Haddadeh, R, Jahromi, M
core  

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

Molecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone, James Dunford, Eleanor Calcutt, Vicki Gamble, Filiz Senbabaoglu Aksu, Lorena Ligammari, Georgina Wherry, Giorgia Gaeta, John C. Christianson, Adrienne M. Flanagan, Udo Oppermann, Adam P. Cribbs   +11 more
wiley   +1 more source

Mobile Paving System (MPS): A New Large Scale Freeform Fabrication Method [PDF]

, 2005
In the last decade, significant opportunities for automation have been identified in the area of construction. Soaring labor and material costs have driven multiple research efforts in construction automation.
Asiabanpour, B., Mata, J., Sriraman, V., Tseng, A., Um, D., Wahed, N.   +5 more
core  

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

Molecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix, Daniel Samaga, Katharina Gehr, Benedek Dankó, Mohamed Schumann, Guido Drexler, Ahmed Alnatsha, Georg Beyer, Ujjwal Mahajan, Martin Selmansberger, Julia Mayerle, Claus Belka, Horst Zitzelsberger, Kirsten Lauber   +13 more
wiley   +1 more source

Investigating alternatives for system architectures to enhance discrete manufacturing

International Journal of Distributed Sensor Networks, 2019
This article investigates the possibility of advancing discrete manufacturing using system architectures that are developed for Collaborative Process Automation Systems.
Sara Afshar, Fereidon Koroorian, Mohammad Ashjaei, Anna Granlund   +3 more
doaj   +1 more source

Generator Power Optimisation for a More-Electric Aircraft by Use of a Virtual Iron Bird [PDF]

, 2006
A prodedure is developed to minimise the generator design power within the electric power system of a future more-/ all-electric aircraft. This allows to save weight on the generators and on other equipment of the electic power system.
Bals, Johann, Pfeiffer, Andreas, Schallert, Christian   +2 more
core