Results 101 to 110 of about 1,565,682 (342)

Desirability to characterize process capability [PDF]

open access: yes
Over the past few years continuously new process capability indices have been developed, most of them with the aim to add some feature missed in former process capability indices.
Jessenberger, J., Weihs, Claus
core  

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

open access: yesFEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman   +2 more
wiley   +1 more source

Monolithic optofluidic chips: from optical manipulation of single cells to quantum sensing of fluids [PDF]

open access: yes, 2014
This paper was presented at the 4th Micro and Nano Flows Conference (MNF2014), which was held at University College, London, UK. The conference was organised by Brunel University and supported by the Italian Union of Thermofluiddynamics, IPEM, the ...
4th Micro and Nano Flows Conference (MNF2014)   +1 more
core  

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

A flexible resubmitted variable sampling plan for product quality determination using the process loss index

open access: yesProduction Engineering Archives
This research aims to develop a flexible resubmitted sampling plan (RSP) incorporating a process loss index for variable inspection. This model will effectively address product specifications that are affected by variations in target value and lot ...
Darmawan Armin   +4 more
doaj   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

Modified Cp and Cpk Indices Based on Left-Truncated Data

open access: yesAxioms
The process capability indices Cp and Cpk are commonly used in industry to evaluate process capability, but they usually require that quality data follow a normal distribution.
Yimin Yin, Bin Yan, Pengfei Liu
doaj   +1 more source

Avoiding Stffness: Perspectives of agile technology diffusion [PDF]

open access: yes, 2015
The increased pervasiveness of Information and Communication Technology (ICT) within the Architecture Engineering and Construction (AEC) sector, not only introduces unparalleled opportunities for enhancing the performance of design/engineering ...
Ezcan, Volkan   +3 more
core  

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