Results 81 to 90 of about 641,383 (315)

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola   +12 more
wiley   +1 more source

Validation of Final Test Equipment Specific to Medical Device [PDF]

open access: yesE3S Web of Conferences
This paper presents the process of evaluating the capability of the testing process using the CMK and Cpk indices. This analysis starts by defining critical parameters and designating a golden sample unit. Data are collected and statistically analyzed in
Ioana Andrei-Cătălin   +1 more
doaj   +1 more source

Computing Multivariate Process Capability Indices With Microsoft Excel [PDF]

open access: yes
In manufacturing industry there is growing interest in measures of process capability under multivariate setting. While there are many statistical packages to assess univariate capability, a current problem with the multivariate measures of capability is
Michele Scagliarini, Raffaele Vermiglio
core   +1 more source

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

open access: yesMolecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg   +43 more
wiley   +1 more source

Repeated exercise stress impairs volitional but not magnetically evoked electromechanical delay of the knee flexors [PDF]

open access: yes, 2012
The effects of serial episodes of fatigue and recovery on volitional and magnetically evoked neuromuscular performance of the knee flexors were assessed in twenty female soccer players during: (i) an intervention comprising 4x35s maximal static exercise;
Bailey, A   +4 more
core   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

Desirability to characterize process capability [PDF]

open access: yes
Over the past few years continuously new process capability indices have been developed, most of them with the aim to add some feature missed in former process capability indices.
Jessenberger, J., Weihs, Claus
core  

Knee joint neuromuscular activation performance during muscle damage and superimposed fatigue [PDF]

open access: yes, 2012
This study examined the concurrent effects of exercise-induced muscle damage and superimposed acute fatigue on the neuromuscular activation performance of the knee flexors of nine males (age: 26.7 ± 6.1yrs; height 1.81 ± 0.05m; body mass 81.2 ± 11.7kg ...
Behm D. G.   +12 more
core   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon   +9 more
wiley   +1 more source

Introducing Triangular Fuzzy Process Capability Indices to Evaluate Performance of Continuous Production Process

open access: yesInternational Journal of Industrial Engineering and Production Research, 2016
Process capability indices (PCIs) can be used as an effective tool for measuring product quality and process performance. In classic quality control there are some limitations which prevent a deep and flexible analysis because of the crisp definition of ...
Rahebe Keshavarzi   +1 more
doaj  

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