Results 101 to 110 of about 21,615,207 (391)
Supporting Dynamic Service Composition at Runtime based on End-user Requirements [PDF]
, 2009 Network-based software application services are receiving a lot of attention in recent years, as observed in developments as Internet of Services, Software as a Service and Cloud Computing.
Ferreira Pires, Luis +2 more
core +2 more sources
Modelling Reservoir Computing with the Discrete Nonlinear Schr\"odinger Equation
, 2018 We formulate, using the discrete nonlinear Schroedinger equation (DNLS), a general approach to encode and process information based on reservoir computing. Reservoir computing is a promising avenue for realizing neuromorphic computing devices.
Boman, Magnus +2 more
core +1 more source
FEBS Letters, EarlyView.Knowing how proteases recognise preferred substrates facilitates matching proteases to applications. The S1′ pocket of protease EA1 directs cleavage to the N‐terminal side of hydrophobic residues, particularly leucine. The S1′ pocket of thermolysin differs from EA's at only one position (leucine in place of phenylalanine), which decreases cleavage ...
Grant R. Broomfield +3 more
wiley +1 more source
Ecosystem-Oriented Distributed Evolutionary Computing
, 2012 We create a novel optimisation technique inspired by natural ecosystems, where the optimisation works at two levels: a first optimisation, migration of genes which are distributed in a peer-to-peer network, operating continuously in time; this process ...
Briscoe, Gerard, De Wilde, Philippe
core +1 more source
Big Data and cloud computing: innovation opportunities and challenges
International Journal of Digital Earth, 2017 Big Data has emerged in the past few years as a new paradigm providing abundant data and opportunities to improve and/or enable research and decision-support applications with unprecedented value for digital earth applications including business ...
C. Yang +4 more
semanticscholar +1 more source
FEBS Letters, EarlyView.In this work, we reveal how different enzyme binding configurations influence the fluorescence decay of NAD(P)H in live cells using time‐resolved anisotropy imaging and fluorescence lifetime imaging microscopy (FLIM). Mathematical modelling shows that the redox states of the NAD and NADP pools govern these configurations, shaping their fluorescence ...
Thomas S. Blacker +8 more
wiley +1 more source
Neutrophil deficiency increases T cell numbers at the site of tissue injury in mice
FEBS Letters, EarlyView.In wild‐type mice, injury or acute inflammation induces neutrophil influx followed by macrophage accumulation. Mcl1ΔMyelo (neutrophil‐deficient) mice lack neutrophils, and in response to muscle injury show fewer macrophages and exhibit strikingly elevated T‐cell numbers, primarily non‐conventional “double‐negative” (DN) αβ and γδ T cells.
Hajnalka Halász +6 more
wiley +1 more source
Acceleration computing process in wavelength scanning interferometry [PDF]
, 2011 The optical interferometry has been widely explored for surface measurement due to the advantages of non-contact and high accuracy interrogation. Eventually, some interferometers are used to measure both rough and smooth surfaces such as white light ...
Gao, F. +2 more
core
Development of visible light‐sensitive human neuropsin (OPN5) via single amino acid substitution
FEBS Letters, EarlyView.The present study determines a key amino acid residue, Lys91, for defining UV sensitivity of human OPN5. Heterologous action spectroscopy of the wild type and K91 mutants of OPN5 in HEK293T cells reveals that substitution of Lys91 with neutral (alanine) or acidic amino acids (glutamic or aspartic acids) causes substantial shifts in spectral sensitivity
Yusuke Sakai +2 more
wiley +1 more source
FEBS Letters, EarlyView.The Arabidopsis mutants hls1 hlh1 and amp1 lamp1 exhibit pleiotropic developmental phenotypes. Although the functions of the causative genes remain unclear, they act in the same genetic pathway and are thought to generate non‐cell‐autonomous signals.
Takashi Nobusawa, Makoto Kusaba
wiley +1 more source