Results 101 to 110 of about 21,828,896 (392)
FEBS Letters, EarlyView.Spinal muscular atrophy (SMA) is a genetic disease affecting motor neurons. Individuals with SMA experience mitochondrial dysfunction and oxidative stress. The aim of the study was to investigate the effect of an antioxidant and neuroprotective substance, ergothioneine (ERGO), on an SMNΔ7 mouse model of SMA.
Francesca Cadile +8 more
wiley +1 more source
Ecosystem-Oriented Distributed Evolutionary Computing
, 2012 We create a novel optimisation technique inspired by natural ecosystems, where the optimisation works at two levels: a first optimisation, migration of genes which are distributed in a peer-to-peer network, operating continuously in time; this process ...
Briscoe, Gerard, De Wilde, Philippe
core +1 more source
FEBS Letters, EarlyView.Phytohormone brassinosteroid‐induced gene regulation by the transcription factor BIL1/BZR1 involves redox‐dependent DNA‐binding alternation and interaction with the transcription factor PIF4. The reduced BIL1/BZR1 dimer binds preferred cis‐elements, while oxidation alters its oligomerization state and disrupts DNA‐binding ability.
Shohei Nosaki +4 more
wiley +1 more source
IEEE Access, 2020 Mobile membranes represent a model of computation inspired from the biological movement provided by endocytosis and exocytosis in the living cells. This paper presents a survey of the results treating the computational power of the mobile membranes ...
Bogdan Aman, Gabriel Ciobanu
doaj +1 more source
Big Data and cloud computing: innovation opportunities and challenges
International Journal of Digital Earth, 2017 Big Data has emerged in the past few years as a new paradigm providing abundant data and opportunities to improve and/or enable research and decision-support applications with unprecedented value for digital earth applications including business ...
C. Yang +4 more
semanticscholar +1 more source
Supporting Dynamic Service Composition at Runtime based on End-user Requirements [PDF]
, 2009 Network-based software application services are receiving a lot of attention in recent years, as observed in developments as Internet of Services, Software as a Service and Cloud Computing.
Ferreira Pires, Luis +2 more
core +2 more sources
Structural dynamics of the plant hormone receptor ETR1 in a native‐like membrane environment
FEBS Letters, EarlyView.The present study unveils the structural and signaling dynamics of ETR1, a key plant ethylene receptor. Using an optimized nanodisc system and solution NMR, we captured full‐length ETR1 in a native‐like membrane environment. Our findings reveal dynamic domain uncoupling and Cu(I)‐induced rigidification, providing the first evidence of metal‐triggered ...
Moritz Lemke +2 more
wiley +1 more source
, 2012 Large-scale universal quantum computing requires the implementation of quantum error correction (QEC). While the implementation of QEC has already been demonstrated for quantum memories, reliable quantum computing requires also the application of ...
D. Gottesman +6 more
core +1 more source
FEBS Letters, EarlyView.Antimicrobial resistance (AMR) is of huge importance, resulting in over 1 million deaths each year. Here, we describe how a new drug, enmetazobactam, designed to help fight resistant bacterial diseases, inhibits a key enzyme (GES‐1) responsible for AMR. Our data show it is a more potent inhibitor than the related tazobactam, with high‐level computation
Michael Beer +10 more
wiley +1 more source
Forcing as a computational process
, 2020 27 pages. Inquiries and commentary can be made at http://jdh.hamkins.org/forcing-as-a-computational-process. Minor updates with version 2.
Hamkins, Joel David +2 more
openaire +2 more sources