Results 111 to 120 of about 21,828,896 (392)
Modeling the risk process in the XploRe computing environment [PDF]
A user friendly approach to modeling the risk process is presented. It utilizes the insurance library of the XploRe computing environment which is accompanied by on-line, hyperlinked and freely downloadable from the web manuals and e-books. The empirical
Krzysztof Burnecki, Rafal Weron
core
FEBS Letters, EarlyView.Mutations in the C9orf72 gene represent the most common genetic cause of amyotrophic lateral sclerosis (ALS), a fatal neurodegenerative disease. Using patient‐derived neurons and C. elegans models, we find that the nucleoporin Nup107 is dysregulated in C9orf72‐associated ALS. Conversely, reducing Nup107 levels mitigates disease‐related changes.
Saygın Bilican +7 more
wiley +1 more source
FEBS Letters, EarlyView.Single‐cell RNA sequencing reveals an opposite role of SLPI in basal tumors based on metastatic spread, along with shared activation of specific regulons in cancer cells and mature luminal lactocytes, as well as downregulation of MALAT1 and NEAT1 in the latter.
Pietro Ancona +4 more
wiley +1 more source
Imeglimin attenuates liver fibrosis by inhibiting vesicular ATP release from hepatic stellate cells
FEBS Letters, EarlyView.Imeglimin, at clinically relevant concentrations, inhibits vesicular ATP accumulation and release from hepatic stellate cells, thereby attenuating purinergic signaling and reducing fibrogenic activation. This mechanism reveals a newly identified antifibrotic action of imeglimin beyond glycemic control.
Seiji Nomura +8 more
wiley +1 more source
Cybernetics and Information Technologies, 2019 This paper introduces an application of an Ant Colony Optimization algorithm to optimize the parameters in the design of a type of nonlinear robust control algorithm based on coefficient diagram method and backstepping strategy with nonlinear observer ...
Haouari Fouad +3 more
doaj +1 more source
Revealing the structure of land plant photosystem II: the journey from negative‐stain EM to cryo‐EM
FEBS Letters, EarlyView.Advances in cryo‐EM have revealed the detailed structure of Photosystem II, a key protein complex driving photosynthesis. This review traces the journey from early low‐resolution images to high‐resolution models, highlighting how these discoveries deepen our understanding of light harvesting and energy conversion in plants.
Roman Kouřil
wiley +1 more source
Scientific ReportsThis paper presents a machine learning (ML) model designed to track the maximum power point of standalone Photovoltaic (PV) systems. Due to the nonlinear nature of power generation in PV systems, influenced by fluctuating weather conditions, managing ...
Samir A. Hamad +4 more
doaj +1 more source
RAD50 missense variants differentially affect the DNA damage response and mitotic progression
FEBS Letters, EarlyView.RAD50 incorporates into the MRN complex and initiates the DNA damage response. Furthermore, RAD50 promotes mitotic progression. RAD50 missense variants capable of forming an MRN complex supported the DNA damage response and mitotic features to different extents in complementation experiments, indicating these functions are separable and might impact ...
Hanna Redeker +9 more
wiley +1 more source
Applied Sciences, 2019 Cloud computing services that provide computing resources to users through the Internet also provide computing resources in a virtual machine form based on virtualization techniques.
Jueun Jeon +2 more
doaj +1 more source
Fog Computing for the Internet of Things
ACM Trans. Internet Techn., 2019 Research in the Internet of Things (IoT) conceives a world where everyday objects are connected to the Internet and exchange, store, process, and collect data from the surrounding environment.
C. Puliafito +4 more
semanticscholar +1 more source