Results 241 to 250 of about 2,519,267 (345)

Overview of molecular signatures of senescence and associated resources: pros and cons

FEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas, Sylvia Vagena, Pavlos Pantelis, Giorgos Theocharous, Russel Petty, Konstantinos Evangelou, Vassilis G. Gorgoulis   +6 more
wiley   +1 more source

Optogenetically enhanced physical reservoir computing with <i>in vitro</i> neural networks for obstacle avoidance. [PDF]

J Biomed Opt
Deng Y, Li J, Lin Y, Lu Z, Gui L, Sha L, Sun X, Lan Y, Xu Q, Xu K.   +9 more
europepmc   +1 more source

A different way to formulate computing: Optimal Adiabatic Scaling (OAS) and Processor‐In‐Memory‐and‐Storage (PIMS).

, 2014
Erik P. DeBenedictis
openalex   +1 more source

A Pathway to Near Tissue Computing through Processing-in-CTIA Pixels for Biomedical Applications [PDF]

Zihan Yin, Chengwei Zhou, Gourav Datta, Akhilesh Jaiswal   +3 more
openalex   +1 more source

Molecular determinants of signal transduction in tropomyosin receptor kinases

FEBS Open Bio, EarlyView.
Tropomyosin receptor kinases control critical neuronal functions, but how do the same receptors produce diverse cellular responses? This review explores the structural mechanisms behind Trk signaling diversity, focusing on allosteric modulation and ligand bias.
Giray Enkavi
wiley   +1 more source

Neuromorphic Devices: Materials, Structures and Bionic Applications. [PDF]

Nanomaterials (Basel)
Zhu L, Wan Q.
europepmc   +1 more source

ATG4B is required for mTORC1‐mediated anabolic activity and is associated with clinical outcomes in non‐small cell lung cancer

FEBS Open Bio, EarlyView.
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan, Bethany C. Guerra, Selina Uranga, Jessica M. Cardin, Steven E. Riechman, Mariana Janini Gomes, James D. Fluckey   +6 more
wiley   +1 more source

Ultrahigh-precision analog computing using memory-switching geometric ratio of transistors. [PDF]

Sci Adv
Yangdong XJ, Wang C, Zhao Y, Wang ZC, Yang Z, Liu Z, Yu W, Zeng Z, Wang S, Wei W, Shen Y, Kong D, Ding S, Wang X, Pan C, Liang SJ, Miao F.   +16 more
europepmc   +1 more source

Diabetes‐induced vascular calcification is associated with low pyrophosphate and its oral supplementation prevents calcification in diabetic mice

FEBS Open Bio, EarlyView.
Induction of diabetes in three different mouse strains uniformly resulted in an increase in TNAP activity and a reduction in pyrophosphate (PPi) in the circulation. Inhibition of TNAP restored plasma PPi. Diabetes‐induced calcification in the media layer of the aorta was detected only in the Abcc6−/− strain, which is predisposed to ectopic ...
Krisztina Fülöp, Eszter Kozák, Natália Tőkési, Lilian Kocsis, Anikó Kelemen, Zsuzsanna Geszti, Adriána Kutás, Mariann Harangi, Ágnes Diószegi, Zsolt Rapi, József Balla, Olivier Le Saux, András Váradi, Viola Pomozi   +13 more
wiley   +1 more source

Developing a quantum computing model for sequence annotation of interferon protein. [PDF]

Comput Struct Biotechnol J
Li B, Yu Y, Ma F, Dong Z, Zhang L.
europepmc   +1 more source