Results 91 to 100 of about 21,427,686 (296)
A Designer’s Role in Inclusive Design Processes [PDF]
, 2019 Today’s world is in the midst of a material and immaterial exchange process, one of discussion and synergic use of abilities. This begs the question of what role design could possibly play in these conditions and what procedures should a designer put in place in order to attempt to give plausible answers to the new relationships that connect people and
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Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
EnergiesThis review provides a comprehensive analysis of advanced control strategies and operational optimization of energy systems, focusing on heat pumps, with an emphasis on their role in enhancing energy efficiency and operational flexibility.
Konstantinos Sittas +2 more
doaj +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
A Standard Design Process for Sustainable Design
Procedia Computer Science, 2015 AbstractThis exploratory research examined the degree of adoption and impact of the concepts of Building Information Model (BIM), Integrated Project Delivery (IPD), Integrated Design Process (IDP) and Building Energy Simulation (BES) on the design processes of advanced architectural firms when executing sustainable design. Six offices identified by the
openaire +2 more sources
, 2022 This book aims at encompassing the panorama of design tools being developed, tested and adopted by researchers and professors at the Department of Design of Politecnico di Milano.
Bruno, Carmen +4 more
core
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
CrystalsThe recycling of polyethylene terephthalate (PET) is gaining increasing importance, as it enables the conversion of plastic waste into valuable raw materials and contributes to a circular economy.
Lukas Seppelfricke +4 more
doaj +1 more source
Design Considerations for AR-Enabled Human-Robot Collaboration in Fabrication-Centric Architectural Design Process: A Co-design Approach [PDF]
The emergence of collaborative robotics presents an opportunity for architectural designers to safely engage in design and fabrication through human-robot collaboration (HRC).
Donovan, Jared +13 more
core +2 more sources
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source