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Understanding requirements engineering process: a challenge for practice and education [PDF]
Reviews of the state of the professional practice in Requirements Engineering (RE) stress that the RE process is both complex and hard to describe, and suggest there is a significant difference between competent and "approved" practice.
Armarego, J., Nguyen, L., Swatman, P.
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A Boxology of Design Patterns for Hybrid Learning and Reasoning Systems [PDF]
We propose a set of compositional design patterns to describe a large variety of systems that combine statistical techniques from machine learning with symbolic techniques from knowledge representation.
Teije, Annette ten, van Harmelen, Frank
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eXplainable Artificial Intelligence in Process Engineering: Promises, Facts, and Current Limitations
Artificial Intelligence (AI) has been swiftly incorporated into the industry to become a part of both customer services and manufacturing operations.
Luigi Piero Di Bonito+4 more
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Modelling and managing reliability growth during the engineering design process [PDF]
[This is a keynote speech presented at the 2nd International Conference on Design Engineering and Science, discussing modelling and managing reliability growth during the engineering process.] Reliability is vital for safe and efficient operation of ...
Quigley, J.L., Walls, Lesley
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A Product Line Systems Engineering Process for Variability Identification and Reduction
Software Product Line Engineering has attracted attention in the last two decades due to its promising capabilities to reduce costs and time to market through reuse of requirements and components.
Dickerson, Charles+4 more
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TRAF2 binds to TIFA via a novel motif and contributes to its autophagic degradation
TRAF family members couple receptor signalling complexes to downstream outputs, but how they interact with these complexes is not always clear. Here, we show that during ADP‐heptose signalling, TRAF2 binding to TIFA requires two short sequence motifs in the C‐terminal tail of TIFA, which are distinct from the TRAF6 binding motif.
Tom Snelling+4 more
wiley +1 more source
Exposure to common noxious agents (1), including allergens, pollutants, and micro‐nanoplastics, can cause epithelial barrier damage (2) in our body's protective linings. This may trigger an immune response to our microbiome (3). The epithelial barrier theory explains how this process can lead to chronic noncommunicable diseases (4) affecting organs ...
Can Zeyneloglu+17 more
wiley +1 more source
Three‐dimensional (3D) biological systems have become key tools in lymphoma research, offering reliable in vitro and ex vivo platforms to explore pathogenesis and support precision medicine. This review highlights current 3D non‐Hodgkin lymphoma models, detailing their features, advantages, and limitations, and provides a broad perspective on future ...
Carla Faria+3 more
wiley +1 more source
From omics to AI—mapping the pathogenic pathways in type 2 diabetes
Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan+2 more
wiley +1 more source
Engineering design project : series 2 [PDF]
This book is a compilation of engineering design projects which illustrates a detail explanation on the design process including all tools and methods involved in each design stage.
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