Results 91 to 100 of about 23,404,019 (398)

Functional variation among LPMOs revealed by the inhibitory effects of cyanide and buffer ions

open access: yesFEBS Letters, EarlyView.
This study addresses the inhibition of lytic polysaccharide monooxygenases (LPMOs) by cyanide and explains how and why the magnitude of observed inhibitory effects depends on the way LPMO reactions are setup and on the type of LPMO. Enzymes known as lytic polysaccharide monooxygenases (LPMOs) are mono‐copper polysaccharide‐degrading peroxygenases that ...
Ole Golten   +10 more
wiley   +1 more source

The Impact of Engineering Design Process in Teaching and Learning to Enhance Students' Science Problem-Solving Skills [PDF]

open access: yes, 2018
This study aimed to determine the impact of the integration of engineering design process (asking, imagining, planning, creating and improving) in an electrical & magnetism module to improve problem-solving skills in physics among secondary school ...
Halim, L. (Lilia)   +3 more
core  

Supporting reflection and creative thinking by carers of older people with dementia [PDF]

open access: yes, 2011
This vision paper frames requirements engineering as a creative problem solving process. Its purpose is to enable requirements researchers and practitioners to recruit relevant theories, models, techniques and tools from creative problem solving to ...
Jones, S.   +6 more
core   +1 more source

Towards a Systems Engineering Essence [PDF]

open access: yesarXiv, 2015
SEMAT/OMG Essence provides a powerful Language and a Kernel for describing software development processes. How can it be tweaked to apply it to systems engineering methods description? We must harmonize Essence and various systems engineering standards in order to provide a more formal system approach to obtaining a Systems Engineering Essence. In this
arxiv  

Ablation of LRP6 in alpha‐smooth muscle actin‐expressing cells abrogates lung inflammation and fibrosis upon bleomycin‐induced lung injury

open access: yesFEBS Letters, EarlyView.
Low‐density lipoprotein receptor‐related protein 6 (LRP6) is a key receptor for the Wnt antagonist Dickkopf1 (DKK1). DKK1 protein expression is induced in a bleomycin (BLM)‐induced lung injury model. We show that DKK1 induces proinflammatory and profibrotic genes in lung fibroblasts.
Eun‐Ah Sung   +6 more
wiley   +1 more source

USE OF NEURAL NETWORKS IN PROCESS ENGINEERING Thermodynamics, diffusion, and process control and simulation applications

open access: yesCT&F Ciencia, Tecnología & Futuro, 1998
This article presents the current status of the use of Artificial Neural Networks (ANNs) in process engineering applications where common mathematical methods do not completely represent the behavior shown by experimental observations, results, and plant
F OTERO
doaj  

Generative artificial intelligence in chemical engineering spans multiple scales

open access: yesFrontiers in Chemical Engineering
Recent advances in generative artificial intelligence (GenAI), particularly large language models (LLMs), are profoundly impacting many fields. In chemical engineering, GenAI plays a pivotal role in the design, scale-up, and optimization of chemical and ...
Benjamin Decardi-Nelson   +6 more
doaj   +1 more source

Requirements Engineering as Creative Problem Solving: A Research Agenda for Idea Finding [PDF]

open access: yes, 2010
This vision paper frames requirements engineering as a creative problem solving process. Its purpose is to enable requirements researchers and practitioners to recruit relevant theories, models, techniques and tools from creative problem solving to ...
Jones, S.   +5 more
core   +1 more source

Guidelines for Systematic Mapping Studies in Security Engineering [PDF]

open access: yesarXiv, 2018
Security engineering in the software lifecycle aims at protecting information and systems to guarantee confidentiality, integrity, and availability. As security engineering matures and the number of research papers grows, there is an increasing need for papers that summarize results and provide an overview of the area. A systematic mapping study "maps"
arxiv  

Characteristics of the Kelch domain containing (KLHDC) subfamily and relationships with diseases

open access: yesFEBS Letters, EarlyView.
The Kelch protein superfamily includes 63 members, with the KLHDC subfamily having 10 proteins. While their functions are not fully understood, recent advances in KLHDC2's structure and role in protein degradation have highlighted its potential for drug development, especially in PROTAC therapies.
Courtney Pilcher   +6 more
wiley   +1 more source

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