Results 81 to 90 of about 5,351,373 (348)

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Review of Integrated Management Systems to Re-Engineer Existing Nonconformances Troubleshooting System

open access: yesSafety
Total quality management (TQM) is a strategic philosophy that has adopted kaizen activities which drives the business to carry out activities effectively to yield the best desired output, hence, a profitable organization.
Matshidiso Moso   +1 more
doaj   +1 more source

The Impact of Engineering Design Process in Teaching and Learning to Enhance Students' Science Problem-Solving Skills [PDF]

open access: yes, 2018
This study aimed to determine the impact of the integration of engineering design process (asking, imagining, planning, creating and improving) in an electrical & magnetism module to improve problem-solving skills in physics among secondary school ...
Halim, L. (Lilia)   +3 more
core  

Towards a Security Engineering Process Model for Electronic Business Processes

open access: yes, 2012
Business process management (BPM) and accompanying systems aim at enabling enterprises to become adaptive. In spite of the dependency of enterprises on secure business processes, BPM languages and techniques provide only little support for security ...
Eichler, Jörn
core   +3 more sources

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

FRENCH-ROMANIAN WORKSHOP “PROMOTING GREEN CHEMISTRY” 06 – 07 JULY 2010 – ORLEANS, FRANCE

open access: yesScientific Study & Research: Chemistry & Chemical Engineering, Biotechnology, Food Industry, 2011
The French-Romanian Workshop "Promotion of Green Chemistry - Applications in Organic Synthesis, Analytical Chemistry and Process Engineering" organized by the Research Center “Applied Chemistry and Process Engineering” of the "Vasile Alecsandri ...
Irina-Claudia Alexa
doaj  

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Delphi/AHP-Based Method for Biomass Sustainable Assessment in the Sugar Industry

open access: yesEng
Multi-criteria methods are highly attractive tools to address the inherent complexity of evaluating problems in various scientific areas. The combination of methods such as Delphi/AHP is emerging as a robust alternative to evaluate the sustainability of ...
Reinier Jiménez Borges   +7 more
doaj   +1 more source

Data Engineering for the Analysis of Semiconductor Manufacturing Data [PDF]

open access: yes, 1995
We have analyzed manufacturing data from several different semiconductor manufacturing plants, using decision tree induction software called Q-YIELD. The software generates rules for predicting when a given product should be rejected.
Turney, Peter
core   +2 more sources

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