Results 91 to 100 of about 1,245,911 (259)

Lyophilization Process Engineering and Thermostability of ID93 + GLA-SE, a Single-Vial Adjuvanted Subunit Tuberculosis Vaccine Candidate for Use in Clinical Studies. [PDF]

Front Drug Deliv, 2022
Dutill TS, Archer MC, McCollum J, Press C, McNeill L, Hawkins L, Phan T, Laursen E, Cabullos R, Bouchard L, Castro RJ, Lin MW, Roco J, Blois C, Adeagbo B, Guderian JA, Gerhardt A, Beckmann AM, Trappler EH, Kramer RM, Fox CB.   +20 more
europepmc   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Optimization of High‐κ HfO2 Transistor Dielectrics by Atomic Layer Deposition as an Enabler of Novel Thin‐Film Circuits and Sensors

Advanced Physics Research
This study explores the integration of atomic layer deposited (ALD) HfO2 dielectric films with solution‐processed In2O3 semiconductor channel, thin‐film transistors (TFTs) for a silicon chip‐free temperature sensor label. The inclusion of the HfO2 high‐κ
Matin Forouzmehr, Hamed Pourkheirollah, Fabio Leite, Elin Howard, Sunil Kumar Behera, Amit Tewari, Jarmo Laakso, Kimmo Lahtonen, Cesar A. T. Laia, A. Jorge Parola, Phillipe Marrec, Donald Lupo, Paul. R. Berger   +12 more
doaj   +1 more source

Correction to: Genetic and process engineering strategies for enhanced recombinant N-glycoprotein production in bacteria. [PDF]

Microb Cell Fact, 2021
Pratama F, Linton D, Dixon N.
europepmc   +1 more source

Phosphoinositides and inositol phosphates as molecular glues

FEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry, Alexander J. Cutright, Mong Na Claire Loi, Jessica Martin, Joseph W. Gilligan, Jakub N. Kubina, Michael J. Arambula, Susanna Tanada Palmu, Daniella Zhou, Raymond D. Blind   +9 more
wiley   +1 more source

Process Engineering of Biopharmaceutical Production in Moss Bioreactors via Model-Based Description and Evaluation of Phytohormone Impact. [PDF]

Front Bioeng Biotechnol, 2022
Ruiz-Molina N, Parsons J, Schroeder S, Posten C, Reski R, Decker EL.   +5 more
europepmc   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source

Genetic and process engineering strategies for enhanced recombinant N-glycoprotein production in bacteria. [PDF]

Microb Cell Fact, 2021
Pratama F, Linton D, Dixon N.
europepmc   +1 more source

Mixed‐class J‐domain protein scaffolds promote expanded aggregate handling and multivalent Hsp70 engagement during functional disaggregase assembly

FEBS Letters, EarlyView.
Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley   +1 more source

Elimination of Escherichia coli in a Packed Column Containing Jujube Seed Kernel Granular Activated Carbon Coated With Silver Nanoparticles (Ag-NPs/GAC)

Journal of Chemistry
This study aims to develop a filter material capable of inhibiting bacterial growth and eliminating microorganisms from filtered water. Granular activated carbon (GAC) was prepared from jujube seed kernels by a chemical activation method whereby the ...
Ngounou M. Kameni, Mengue Nsoe, Esegni V. Amba, Guillaume Kofa, Koungou S. Ndi, Guifo J. Kayem   +5 more
doaj   +1 more source