Optimizing lipid-lowering synbiotics: strain screening, synergistic consortium formulation, prebiotic modulation, and freeze-drying process engineering for enhanced stability and efficacy. [PDF]
Food Chem (Oxf)Zhu W, Borjihan Q, Chen Y, Xia Y.
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The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity
Molecular Oncology, EarlyView.Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli +7 more
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Integrated Materials Design and Process Engineering for n-Type Polymer Thermoelectrics. [PDF]
JACS AuDeng XY, Zhang Z, Lei T.
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Time and Processes: Towards Engineering Temporal Requirements
, 2021 Johann Eder +2 more
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Targeting p38α in cancer: challenges, opportunities, and emerging strategies
Molecular Oncology, EarlyView.p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
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Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin
Molecular Oncology, EarlyView.Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon +4 more
wiley +1 more source
Enhanced Production of Antimicrobial Pyocyanin Using Electromagnetic Fields and Carbon Nanotubes
Nanotechnology, Science and ApplicationsJoanna Honselmann genannt Humme,1 Kamila Dubrowska,1 Dawid Sołoducha,1 Tomasz Borowski,1 Adrian Augustyniak,1,2 Rafał Rakoczy1,2 1Department of Chemical and Process Engineering, Faculty of Chemical Technology and Engineering, West ...
Honselmann genannt Humme J +5 more
doaj
Research on the evaluation method of whole process engineering consulting service modes based on uncertain multiple-attribute group decision-making. [PDF]
HeliyonWang X, Hou Y, Peng J, Hu J.
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Process engineering of pH tolerant Ustilago cynodontis for efficient itaconic acid production. [PDF]
Microb Cell Fact, 2019 Hosseinpour Tehrani H +4 more
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