Results 41 to 50 of about 1,219,258 (290)

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

FEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang, Satoshi Hashimoto, Sota Ito, Chisato Kikuguchi, Miho Hoshi, Kiyoshi Yamaguchi, Yoichi Furukawa, Toru Suzuki, Toshifumi Inada   +8 more
wiley   +1 more source

eXplainable Artificial Intelligence in Process Engineering: Promises, Facts, and Current Limitations

Applied System Innovation
Artificial Intelligence (AI) has been swiftly incorporated into the industry to become a part of both customer services and manufacturing operations.
Luigi Piero Di Bonito, Lelio Campanile, Francesco Di Natale, Michele Mastroianni, Mauro Iacono   +4 more
doaj   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

FEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Two-dimensional molybdenum carbide 2D-Mo2C as a superior catalyst for CO2 hydrogenation

Nature Communications, 2021
The development of robust and efficient catalysts for CO2 hydrogenation to value-added chemicals is an urgent task. Here the authors report two-dimensional carbide catalyst based on earth-abundant molybdenum that hydrogenates CO2 with high activity ...
Hui Zhou, Zixuan Chen, Evgenia Kountoupi, Athanasia Tsoukalou, Paula M. Abdala, Pierre Florian, Alexey Fedorov, Christoph R. Müller   +7 more
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

The improvement of maintenance service for traction networks equipment on the base of process approach

Nauka ta progres transportu, 2014
Purpose. The new methods development for improving the maintenance service for equipment of traction networks in order to increase its efficiency and quality. Methodology.
D. V. Mironov
doaj   +1 more source

Production of a 135-residue long N-truncated human keratinocyte growth factor 1 in Escherichia coli

Microbial Cell Factories, 2023
Background Palifermin (trade name Kepivance®) is an amino-terminally truncated recombinant human keratinocyte growth factor 1 (KGF-1) with 140 residues that has been produced using Escherichia coli to prevent and treat oral mucositis following radiation ...
Young Su Kim, Hye-Jeong Lee, Gabriella Aphrodita Handoko, Jaehui Kim, Seong-Bo Kim, Minho Won, Jung-Ho Park, Jungoh Ahn   +7 more
doaj   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

USE OF NEURAL NETWORKS IN PROCESS ENGINEERING Thermodynamics, diffusion, and process control and simulation applications

CT&F Ciencia, Tecnología & Futuro, 1998
This article presents the current status of the use of Artificial Neural Networks (ANNs) in process engineering applications where common mathematical methods do not completely represent the behavior shown by experimental observations, results, and plant
F OTERO
doaj  

A Sustainable Chemicals Manufacturing Paradigm Using CO2 and Renewable H2

iScience, 2020
Summary: The chemical industry must decarbonize to align with UN Sustainable Development Goals. A shift toward circular economies makes CO2 an attractive feedstock for producing chemicals, provided renewable H2 is available through technologies such as ...
Rajesh Reddy Bommareddy, Yanming Wang, Nicole Pearcy, Martin Hayes, Edward Lester, Nigel P. Minton, Alex V. Conradie   +6 more
doaj   +1 more source