Results 81 to 90 of about 5,272,056 (327)

Part 2: pushing the envelope. A process perspective for architecture, engineering and construction [PDF]

open access: yes, 2015
In this article, I am building on an emerging 'process view of nature' and how biological membranes emerge through the combined action of (locally) autonomous construction agents.
Soar, R
core   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

A Product Line Systems Engineering Process for Variability Identification and Reduction

open access: yes, 2018
Software Product Line Engineering has attracted attention in the last two decades due to its promising capabilities to reduce costs and time to market through reuse of requirements and components.
Dickerson, Charles   +4 more
core   +1 more source

Substrate specificity of Burkholderia pseudomallei multidrug transporters is influenced by the hydrophilic patch in the substrate‐binding pocket

open access: yesFEBS Letters, EarlyView.
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley   +1 more source

Review of Integrated Management Systems to Re-Engineer Existing Nonconformances Troubleshooting System

open access: yesSafety
Total quality management (TQM) is a strategic philosophy that has adopted kaizen activities which drives the business to carry out activities effectively to yield the best desired output, hence, a profitable organization.
Matshidiso Moso   +1 more
doaj   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

open access: yesFEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang   +9 more
wiley   +1 more source

FRENCH-ROMANIAN WORKSHOP “PROMOTING GREEN CHEMISTRY” 06 – 07 JULY 2010 – ORLEANS, FRANCE

open access: yesScientific Study & Research: Chemistry & Chemical Engineering, Biotechnology, Food Industry, 2011
The French-Romanian Workshop "Promotion of Green Chemistry - Applications in Organic Synthesis, Analytical Chemistry and Process Engineering" organized by the Research Center “Applied Chemistry and Process Engineering” of the "Vasile Alecsandri ...
Irina-Claudia Alexa
doaj  

Mapping customer needs to engineering characteristics: an aerospace perspective for conceptual design

open access: yes, 2014
Designing complex engineering systems, such as an aircraft or an aero-engine, is immensely challenging. Formal Systems Engineering (SE) practices are widely used in the aerospace industry throughout the overall design process to minimise the overall ...
Bertoni, M.   +3 more
core   +3 more sources

Mechanisms of parasite‐mediated disruption of brain vessels

open access: yesFEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira   +3 more
wiley   +1 more source

Delphi/AHP-Based Method for Biomass Sustainable Assessment in the Sugar Industry

open access: yesEng
Multi-criteria methods are highly attractive tools to address the inherent complexity of evaluating problems in various scientific areas. The combination of methods such as Delphi/AHP is emerging as a robust alternative to evaluate the sustainability of ...
Reinier Jiménez Borges   +7 more
doaj   +1 more source

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