Results 101 to 110 of about 6,451,411 (344)

Novel Genetic Risk Factor Identified for L‐Asparaginase‐Induced Pancreatitis in Pediatric Patients With Cancer

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background L‐asparaginase is a critical component in treatment protocols for pediatric acute lymphoblastic leukemia. Acute pancreatitis reactions can necessitate delays and, in some cases, discontinuation of L‐asparaginase, which compromises outcomes.
Edward J. Raack   +39 more
wiley   +1 more source

Incremental learning of independent, overlapping, and graded concept descriptions with an instance-based process framework [PDF]

open access: yes, 1989
Supervised learning algorithms make several simplifying assumptions concerning the characteristics of the concept descriptions to be learned. For example, concepts are often assumed to be (1) defined with respect to the same set of relevant attributes ...
Aha, David W.
core  

Upacicalcet: A Novel Intravenous Calcimimetic Agent for Patients Undergoing Hemodialysis With Secondary Hyperparathyroidism

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Secondary hyperparathyroidism (SHPT) is a common complication in patients receiving maintenance dialysis, driven by calcium and phosphate metabolism disturbances. Calcimimetics are central to the management of SHPT by enhancing calcium‐sensing receptor sensitivity and reducing parathyroid hormone secretion.
Fumihiko Koiwa   +3 more
wiley   +1 more source

A process-aware framework to support Process Mining from blockchain applications

open access: yesJournal of King Saud University: Computer and Information Sciences
Several studies were conducted to demonstrate the application of Process Mining (PM) techniques to Ethereum-compatible application event data. However, the availability of event data is constrained by the application’s process awareness, which is under ...
Fouzia Alzhrani   +2 more
doaj   +1 more source

The barriers and facilitators to the implementation of National Clinical Programmes in Ireland: using the MRC framework for process evaluations

open access: yesBMC Health Services Research, 2018
Background A major healthcare reform agenda in Ireland is underway which underpins the establishment of a series of National Clinical Programmes (NCPs), which aim to take an evidence based approach to improve quality, access and value.
Catherine D. Darker   +3 more
doaj   +1 more source

Revealing the structure of land plant photosystem II: the journey from negative‐stain EM to cryo‐EM

open access: yesFEBS Letters, EarlyView.
Advances in cryo‐EM have revealed the detailed structure of Photosystem II, a key protein complex driving photosynthesis. This review traces the journey from early low‐resolution images to high‐resolution models, highlighting how these discoveries deepen our understanding of light harvesting and energy conversion in plants.
Roman Kouřil
wiley   +1 more source

Metaheuristic framework of the value creation process [PDF]

open access: yesمطالعات مدیریت راهبردی, 2019
The aim of current fundamental research is designing and explaining of metaheuristic framework of the value creation process. In this regard, in the first phase, based on the extensive, deep and systematic study of theoretical foundations, 9 dimensions ...
Masoud Lajevardi   +3 more
doaj  

Supporting process reuse in PROMENADE [PDF]

open access: yes, 2002
Process reuse (the ability to construct new processes by assembling already built ones) and process harvesting (the ability to build generic processes that may be further reused, from existing ones) are two crucial issues in process technology.
Franch Gutiérrez, Javier   +1 more
core   +1 more source

Mapping the evolution of mitochondrial complex I through structural variation

open access: yesFEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin   +2 more
wiley   +1 more source

METHODOLOGY FRAMEWORK FOR PROCESS INTEGRATION AND SERVICE MANAGEMENT

open access: yesJournal of Information and Organizational Sciences, 2007
History of information systems development was driven by business system's functions automation and mergers and acquisitions - business subjects integration into a whole.
Darko Galinec, Slavko Vidović
doaj  

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