Results 171 to 180 of about 6,451,411 (344)
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard +5 more
wiley +1 more source
GPMelt: A hierarchical Gaussian process framework to explore the dark meltome of thermal proteome profiling experiments. [PDF]
Le Sueur C, Rattray M, Savitski M.
europepmc +1 more source
PROGame: A process framework for serious game development for motor rehabilitation therapy. [PDF]
Amengual Alcover E +2 more
europepmc +1 more source
Understanding of the test phases, definition of inputs/outputs, aims of tests etc allowing the optimisation for certain field tests ...
openaire +1 more source
Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed +10 more
wiley +1 more source
Codiscovering graphical structure and functional relationships within data: A Gaussian Process framework for connecting the dots. [PDF]
Bourdais T +5 more
europepmc +1 more source
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source

