Results 151 to 160 of about 35,353,269 (300)

The refinement of repeated exact time-to-event modeling: methodological refinements and implementation in NONMEM^® -part I. [PDF]

Front Pharmacol
Seo J, Lim HS.
europepmc   +1 more source

APOBEC3 activity and DNA polymerase‐ε deficiency are associated with distinct IDH1 R132 hotspot mutations

Molecular Oncology, EarlyView.
Isocitrate dehydrogenase 1 (IDH1) mutations are highly recurrent in multiple human cancer types, including cholangiocarcinoma and glioma. IDH1 R132C is the most common IDH1 mutation in cholangiocarcinoma and likely arises from APOBEC3A‐ or APOBEC3B‐mediated deamination.
Kelly E. Butler, Bilal A. Lone, Ecem Unal, A. Rouf Banday   +3 more
wiley   +1 more source

Moral Hazard, Adverse Selection and Health Expenditures: A Semiparametric Analysis [PDF]

Theoretical models predict asymmetric information in health insurance markets may generate inefficient outcomes due to adverse selection and moral hazard.
Han Hong, Patrick Bajari, Ahmed Khwaja
core  

Pertuzumab in HER2-positive breast cancer: a systematic review and meta-analysis of randomized controlled trials. [PDF]

Breast Cancer Res Treat
Aboushawareb H, Mohamed AW, Alghzawi HM, Helbawy AE, Tarig A, Zatari H, Hekal MM, Hasan I, Shaban AY.   +8 more
europepmc   +1 more source

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

Molecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu, Yubei He, Nikolaus Berndt, Michael Mülleder, Kathrin Textoris‐Taube, Jing Guo, Matthias Stechele, Justus Ramtke, Shraga Nahum Goldberg, Lynn Jeanette Savic   +9 more
wiley   +1 more source

A note on optimal commodity taxation with moral hazard and separable preferences [PDF]

In this paper we show that differential commodity taxation is superfluous in an economy with moral hazard and separable preferences.Moral Hazard, Separable Preferences, Optimal Commodity ...
Francesco Ruscitti, Luca Panaccione
core  

Exploring successful implementation of occupational therapy led home fall-hazard reduction interventions. [PDF]

Aust Occup Ther J
Melchert S, Franklin R, Lowrie D.
europepmc   +1 more source

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

Molecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso, Md Shohel Ul Islam, Rosa M Xicola, Raj Ramesar, Xavier Llor, Sinclair Steele   +5 more
wiley   +1 more source

Diffusion Processes and Event History Analysis [PDF]

Several authors (e. g., Brüderl, Diekmann, Yamaguchi) derive hazard rate models of event history analysis from social diffusion processes. This paper also focuses on the integration of diffusion research and survival analysis.
Norman Braun, Henriette Engelhardt
core  

Hospital Preparedness for CBRNE Threats in Iran: A Qualitative Policy Analysis of Risk Assessment Using the Walt and Gilson Framework. [PDF]

J Healthc Leadersh
Javan Biparva A, Nasiri T, Nasiri A, Karamali M.   +3 more
europepmc   +1 more source