Results 181 to 190 of about 25,679,349 (377)

The anticancer effect of the HDAC inhibitor belinostat is enhanced by inhibitors of Bcl‐xL or Mcl‐1 in ovarian cancer

Molecular Oncology, EarlyView.
The pan‐HDAC inhibitor belinostat increases the expression of the pro‐apoptotic proteins Bim, Puma, and Noxa and induces apoptosis in ovarian cancer cell lines and patient‐derived tumor organoids when used at high concentrations. Moreover, inhibiting the anti‐apoptotic proteins Bcl‐xL or Mcl‐1 sensitizes these preclinical models to the cytotoxic effect
Cécilia Thomine, Sterenn Guillemot, Louis‐Bastien Weiswald, Romane Florent, Edwige Abeilard, Florence Giffard, Emilie Brotin, Mélanie Briand, Enora Dolivet, Laurent Poulain, Marie Villedieu   +10 more
wiley   +1 more source

Analysis of Yield-Determining Process and Its Application to Yield-Prediction and Culture Improvement of Lowland Rice : LXXXIV. Effects of the different combinations of day- and night-water-temperatures on the growth of rice seedlings.

, 1968
Takayuki Tanaka, Seizo Matsushima, Toyoo Tomita   +2 more
openalex   +2 more sources

Comprehensive omics‐based classification system in adult patients with B‐cell acute lymphoblastic leukemia

Molecular Oncology, EarlyView.
The COMBAT classification system, developed through multi‐omics integration, stratifies adult patients with B‐cell acute lymphoblastic leukemia(B‐ALL) into three molecular subtypes with distinct surface antigen patterns, immune landscape, methylation patterns, biological pathways and prognosis.
Yang Song, Ting Liu, Qishan Hao, Qiuyun Fang, Xiaoyuan Gong, Yan Li, Zheng Tian, Hui Wei, Min Wang, Jianxiang Wang, Tao Cheng, Yingchang Mi   +11 more
wiley   +1 more source

Process improvement using telemedicine consultation to prevent unnecessary interfacility transfers for low-severity blunt head trauma. [PDF]

BMJ Open Qual, 2023
Miles G, Shank C, Quinlan A, Cavender J.
europepmc   +1 more source

Analysis of Yield-Determining Process and Its Application to Yield-Prediction and Culture Improvement of Lowland Rice : LXXIII On the relation between morphological characteristics in receiving light and the percentage of ripened grains under luxurious growth conditions.

, 1965
Seizo Matsushima, Takayuki Tanaka, Takahumi HOSHINO   +2 more
openalex   +2 more sources

Circulating tumor DNA monitoring and blood tumor mutational burden in patients with metastatic solid tumors treated with atezolizumab

Molecular Oncology, EarlyView.
In patients treated with atezolizumab as a part of the MyPathway (NCT02091141) trial, pre‐treatment ctDNA tumor fraction at high levels was associated with poor outcomes (radiographic response, progression‐free survival, and overall survival) but better sensitivity for blood tumor mutational burden (bTMB).
Charles Swanton, Russell W. Madison, Candice Francheska B. Tambaoan, Funda Meric‐Bernstam, Christopher J. Sweeney, Razelle Kurzrock, Howard A. Burris III, David R. Spigel, Hanna Tukachinsky, Jason Hughes, Julia Malato, Bongin Yoo, Tania Szado, Cheryl Schwab, Lincoln W. Pasquina, Amaya Gasco, Katja Schulze, Claire F. Friedman   +17 more
wiley   +1 more source

Process improvement of adeno-associated virus (AAV) production. [PDF]

Front Chem Eng, 2022
Guan JS, Chen K, Si Y, Kim T, Zhou Z, Kim S, Zhou L, Liu XM.   +7 more
europepmc   +1 more source

Process improvement transition authorization IP-14-I: D Reactor full pile loading of bumper fuel elements

, 1961
J.L. Benson
openalex   +1 more source

Dose‐dependent induction of epithelial‐mesenchymal transition in 3D melanoma models by non‐thermal plasma treatment

Molecular Oncology, EarlyView.
Non‐thermal plasma treatment of melanoma cells induced epithelial‐mesenchymal transition (EMT) in a dose‐dependent fashion. This report highlights the critical need to further investigate potential adverse effects of non‐thermal plasma for cancer therapy and to optimize treatment parameters for clinical translation. Despite the promising results of non‐
Eline Biscop, Edgar Cardenas De La Hoz, Hanne Verswyvel, Joey De Backer, Ho Wa Lau, Angela Privat‐Maldonado, Wim Vanden Berghe, Steve Vanlanduit, Evelien Smits, Annemie Bogaerts, Abraham Lin   +10 more
wiley   +1 more source

Nursing Workforce Optimization Study: A Multi-method Evaluation and Process Improvement Intervention for HIV Service Delivery in Tanzania and Zambia. [PDF]

J Assoc Nurses AIDS Care, 2023
Coe M, Kawakyu N, Gimbel S, Nyakuya B, Gabriel N, Leonard D, Chale S, Masiye F, Banda CM, Manangwa S, Moyo G, Boyle G, Freistadt F, Kohler P.   +13 more
europepmc   +1 more source