Results 121 to 130 of about 3,024,432 (308)
Innovation, firm dynamics, and international trade [PDF]
We present a general equilibrium model of the decisions of firms to innovate and to engage in international trade. We use the model to analyze the impact of a reduction in international trade costs on firms' process and product innovative activity.
Andrew Atkeson, Ariel Burstein
core
Rethinking communication in innovation processes: creating space for change in complex systems [PDF]
, 2010 : In innovation studies, communication received explicit attention in the context of studies on the adoption and diffusion of innovation that dominated the field in the 1940-1970 period.
Aarts, M.N.C., Leeuwis, C.
core +1 more source
Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
Innovation and entrepreneurship: structural determinants of competitiveness [PDF]
Innovation and entrepreneurship have become the cornerstone of growth and competitiveness policies. They are both multidimensional, and thus highly complex, concepts.
B. Robert
core
Molecular Oncology, EarlyView.Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
The influence of innovation on firm size [PDF]
This study puts forward the relevance of investigating the relation between innovation and firm size, acknowledging differences between process innovation and product innovation.
Gerrit de Wit, Niels Bosma
core
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
The Process and Product Innovation Strategies Coordination Model based on Competitor Values Framework [PDF]
بهبود مدیریت, 2011 Innovation literature advises the organizations to follow innovation in different aspects of their activities, especially in their products, as a key factor of competitive advantage.
Mohammad Eskandari +2 more
doaj
Molecular Oncology, EarlyView.Translational cancer research and its implementation through competitively selected Comprehensive Cancer Centers across Europe should be the primary policy focus for addressing the increasing cancer burden in Europe and counteract the present main strategy to convert cancer to a chronic disease.
Manuel Heitor +2 more
wiley +1 more source