Results 131 to 140 of about 3,024,432 (308)

PROCESS INNOVATION: HOLISTIC SCENARIOS TO REDUCE TOTAL LEAD TIME [PDF]

open access: yesAnnals: Series on engineering sciences (Academy of Romanian Scientists), 2015
The globalization of markets requires continuous development of business holistic scenarios to ensure acceptable flexibility to satisfy customers. Continuous improvement of supply chain supposes continuous improvement of materials and products lead time ...
Alin POSTEUCĂ, Miron ZAPCIU
doaj  

Organizing Innovation Complementarities between Cross-Functional Teams [PDF]

open access: yes
Cross-functional teams play a potentially important part in the innovation process enabling knowledge sharing, the development of trust and overcoming spatial and organizational barriers.
Giovanni Mangiarotti   +2 more
core  

Living labs as a driver for change in regional television [PDF]

open access: yes, 2014
Traditional television production and distribution organizations are increasingly being challenged by a rapidly changing technological environment. These evolutions force the television industry to leave their comfort zone. This context in mind, regional
Baccarne, Bastiaan, Schuurman, Dimitri
core  

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata   +10 more
wiley   +1 more source

Molecular cancer prevention: Intercepting disease

open access: yesMolecular Oncology, EarlyView.
Oncological practice must evolve, from treating established tumours to proactive cancer interception before clinical manifestation. This will require mechanistic insight into tumour initiation, validated biomarkers of early disease development and redesigned clinical trials, enabling cancer interception to become a core pillar of oncology with the ...
Charlotte Grieco   +2 more
wiley   +1 more source

Ensuring the Abrasive Jet Machining Efficiency Using a Nozzle with a Perforated Insert

open access: yesMachines
Ejector-cleaning devices for abrasive jet machining have various practical applications. The working nozzle is one of the device’s key elements affecting the treated surface quality.
Vadym Baha   +3 more
doaj   +1 more source

Innovation Processes and Factors on Peripheral Regions of Portugal and Spain [PDF]

open access: yes
The innovation is the main locomotive of the economic growth and competitiveness. The understanding about innovation process has updated in last decades.
Natário, Maria Manuela
core   +1 more source

Overview of molecular signatures of senescence and associated resources: pros and cons

open access: yesFEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas   +6 more
wiley   +1 more source

DIFFUSION OF INNOVATION PROCESSES IN HIGH-TECH PRODUCTION OF MEDICAL INDUSTRY OF RUSSIA

open access: yesSovremennye Issledovaniâ Socialʹnyh Problem, 2013
The concept of diffusion of the innovation process is explained, the theoretical aspects and some scientific works of Schumpeter I., Zavlin P.N., Kazantsev L.K., Mindeli L.E., T. Hegerstrand, E.Rodzhersa are reviewed.
Дарья Витальевна Костина
doaj  

Applying Lean in Process Innovation in Healthcare: The Case of Hip Fracture. [PDF]

open access: yesInt J Environ Res Public Health, 2020
Morales-Contreras MF   +4 more
europepmc   +1 more source

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