Results 131 to 140 of about 21,952,323 (349)

Innovation and jobs: evidence from manufacturing firms [PDF]

, 2004
This paper is aimed at structurally assessing the employment effects of the innovative activities of firms. We estimate firm level displacement and compensation effects in a model in which the stock of knowledge capital raises firm relative efficiency ...
García, A., Jaumandreu, Jordi, Rodríguez, César   +2 more
core   +2 more sources

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

Molecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata, Koji Ando, Hirofumi Hasuda, Koshi Mimori, Elizabeth C. Unan, Siddhartha Pulukuri, Aahana Tiku, Allison Berger, Eiji Oki, Ajit Bharti, Tomoharu Yoshizumi   +10 more
wiley   +1 more source

Healthcare as a cultural process: from traditions to innovations

Russian Studies in Culture and Society
Background. The article describes the transformation of understanding culture and medicine in modern society. There is a shift from static to dynamic models, where the patient's individual experience and values become central.
Elena A. Smirnova
doaj   +1 more source

Molecular cancer prevention: Intercepting disease

Molecular Oncology, EarlyView.
Oncological practice must evolve, from treating established tumours to proactive cancer interception before clinical manifestation. This will require mechanistic insight into tumour initiation, validated biomarkers of early disease development and redesigned clinical trials, enabling cancer interception to become a core pillar of oncology with the ...
Charlotte Grieco, Tej Pandya, Charles Swanton   +2 more
wiley   +1 more source

Consensus on innovations and future directions of community first responder schemes in United Kingdom: a national nominal group technique study

Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine
Aim We aimed to achieve consensus among NHS and community stakeholders to identify and prioritise innovations in Community First Responder (CFR) schemes.
Gupteswar Patel, Vanessa Botan, Viet-Hai Phung, Ian Trueman, Mehrshad Parvin Hosseini, Murray D. Smith, Roderick Ørner, Julie Pattinson, Zahid Asghar, Elise Rowan, Robert Spaight, Craig Mortimer, Amanda Brewster, Pauline Mountain, Joshua Miller, Martina Brown, Aloysius Niroshan Siriwardena   +16 more
doaj   +1 more source

The role of actor-networks in the diffusion of management accounting innovations: a comparative study of budgetary control, GP method and Activity-Based Costing in France [PDF]

This research is concerned with the diffusion of management accounting innovations viewed as a process of actor-network building and translation. The aim is to better understand the nature of accounting change.
Nicolas Berland, Simon Alcouffe, Yves Levant   +2 more
core  

Overview of molecular signatures of senescence and associated resources: pros and cons

FEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas, Sylvia Vagena, Pavlos Pantelis, Giorgos Theocharous, Russel Petty, Konstantinos Evangelou, Vassilis G. Gorgoulis   +6 more
wiley   +1 more source

Some factors stimulating innovative development of economy

Путеводитель предпринимателя, 2020
In article classifications of innovations are given: grocery and process, technological and not technological. The factors promoting innovations, and the factors braking innovations are considered; types of innovative activity.

doaj  

Small-scale technologies for energy innovations: role and implication directions [PDF]

Energy innovations with sustainable fundamentals are needed to fulfill energy demands for the coming decades. This leads to a seeking process for new knowledge and technologies in order to create incremental and breakthrough energy innovations.
Knol, W.H.C.
core   +1 more source

Doing Good Today and Better Tomorrow: A Roadmap to High Impact Philanthropy Through Outcome-Focused Grantmaking [PDF]

, 2009
Describes Hewlett's experience with implementing the outcome-focused grantmaking (OFG) process in its environment program as a guide for identifying a portfolio of grants with maximum impact.

core