Results 121 to 130 of about 251,091 (253)
Spillovers in product and process innovation: evidence from manufacturing firms [PDF]
, 2002 This paper proposes a new empirical approach to assess the impact of knowledge spillovers on firms' productivity and demand. I consider a model where process innovations spillovers to other firms raise firms relative efficiency and technological ...
Ornaghi, Carmine
core
MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
Social Innovations in the Process of System Products Development [PDF]
Journal of Economics and Management, 2015 The article shows the essence of social innovation, its place and role in the development of innovative economy and innovative society. Social innovation is described as an active participation, entrepreneurship and creativity of different social groups ...
Anna Olejniczuk-Merta
doaj
The diffusion of process innovations in industrialized and developing countries: a case study of the world textile and steel industries [PDF]
This paper tests the hypothesis that industrial process innovations diffuse more slowly in developing countries than in industrialized countries. The focus of the analysis is on four innovations in the textile and steel industries, selected according to ...
Lücke, Matthias
core
Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae
FEBS Open Bio, EarlyView.Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj +3 more
wiley +1 more source
Realizing Innovations in Service Firms: new organizational forms and supporting processes
This paper describes a number of innovation forms that are of special relevance to firms in the service industry. Not only technological innovations but also organizational innovations have been distinguished.
Elfring, T., Aa, W. van der
core
The process of Eco-innovations
, 2014 This paper describes the process of eco-innovations. The eco-innovation scheme is a part of the legal framework to reduce the CO2 emissions. This eco-innovation scheme and the 6 eligibility criteria are explained.
MALFETTANI Stefano +2 more
core
FEBS Open Bio, EarlyView.CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point +7 more
wiley +1 more source
Innovation as a community-spanning process: strategies to handle path dependency. [PDF]
In this paper, we further develop and apply the notions of path creation and path dependency during technological innovation processes. The process of technological innovation is portrayed as an activity of spanning boundaries between and across ...
Bouwen, René +2 more
core