CDT1 is an essential protein for DNA replication licensing that loads the MCM complex, the eukaryotic replicative DNA helicase, onto replication origins. Overexpression of CDT1 induces cell cycle arrest at the S phase. Here we showed CDT1 inhibits the progression of replication forks by interacting with the MCM complex, leading to the stalling and ...
Takashi Tsuyama +7 more
wiley +1 more source
Process Intensification for Recombinant Marburg Virus Glycoprotein Production Using <i>Drosophila</i> S2 Cells. [PDF]
Göbel S +7 more
europepmc +1 more source
Ultrasound-assisted solution crystallization of fotagliptin benzoate: Process intensification and crystal product optimization. [PDF]
Fang L +6 more
europepmc +1 more source
HSP70 governs permeability and mechanotransduction in primary human endothelial cells
HSP70 chemical inhibition reduces endothelial cell proliferation and increases permeability, the latter supported by normal interendothelial junctional protein distribution. HSP70 also plays a role in shear stress response, a hemodynamic force naturally present in blood vessels and correlated with vessel protection.
Andrea Pinto‐Martinez +5 more
wiley +1 more source
The intensification of mayonnaise production process [PDF]
Syrotuk, O. J., Сиротюк, О. Я.
core
Process intensification of cultivated meat production through microcarrier addition strategy optimisation. [PDF]
Bodiou V +8 more
europepmc +1 more source
Process Intensification of Chemical Exchange Method for Boron Isotope Separation Using Micro-Channel Distillation Technology. [PDF]
Tang Y, Zheng Y, Tian J, Sun J.
europepmc +1 more source
Molecular determinants of signal transduction in tropomyosin receptor kinases
Tropomyosin receptor kinases control critical neuronal functions, but how do the same receptors produce diverse cellular responses? This review explores the structural mechanisms behind Trk signaling diversity, focusing on allosteric modulation and ligand bias.
Giray Enkavi
wiley +1 more source
Perfusion Process Intensification for Lentivirus Production Using a Novel Scale-Down Model. [PDF]
Klimpel M +7 more
europepmc +1 more source
Process intensification and kinetic studies of ultrasound-assisted extraction of flavonoids from peanut shells. [PDF]
Liao J, Guo Z, Yu G.
europepmc +1 more source

